Human Monoclonal Antibodies to a Novel Cluster of Conformational Epitopes on HCV E2 with Resistance to Neutralization Escape in a Genotype 2a Isolate

• Zhen-yong Keck,

  Affiliation Department of Pathology, Stanford University School of Medicine, Stanford, California, United States of America

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• Jinming Xia,

  Affiliation Department of Pathology, Stanford University School of Medicine, Stanford, California, United States of America

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• Yong Wang,

  Affiliation Department of Pathology, Stanford University School of Medicine, Stanford, California, United States of America

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• Wenyan Wang,

  Affiliation Department of Pathology, Stanford University School of Medicine, Stanford, California, United States of America

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• Thomas Krey,

  Affiliation Institut Pasteur, CNRS URA3015, Unite de Virologie Structurale, Paris, France

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• Jannick Prentoe,

  Affiliations Copenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases and Clinical Research Centre, Copenhagen University Hospital, Hvidovre, Denmark, Department of International Health, Immunology and Microbiology, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark

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• Thomas Carlsen,

  Affiliations Copenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases and Clinical Research Centre, Copenhagen University Hospital, Hvidovre, Denmark, Department of International Health, Immunology and Microbiology, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark

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• Angela Ying-Jian Li,

  Affiliation Department of Pathology, Stanford University School of Medicine, Stanford, California, United States of America

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• Arvind H. Patel,

  Affiliation MRC – University of Glasgow Centre for Virus Research, Glasgow, United Kingdom

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• Stanley M. Lemon,

  Affiliation Lineberger Comprehensive Cancer Center and the Division of Infectious Diseases, Department of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

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• Jens Bukh,

  Affiliations Copenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases and Clinical Research Centre, Copenhagen University Hospital, Hvidovre, Denmark, Department of International Health, Immunology and Microbiology, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark

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• Felix A. Rey,

  Affiliation Institut Pasteur, CNRS URA3015, Unite de Virologie Structurale, Paris, France

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• Steven K. H. Foung

  * E-mail: sfoung@stanford.edu

  Affiliation Department of Pathology, Stanford University School of Medicine, Stanford, California, United States of America

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