Group A Streptococcus Secreted Esterase Hydrolyzes Platelet-Activating Factor to Impede Neutrophil Recruitment and Facilitate Innate Immune Evasion

Mengyao Liu; Hui Zhu; Jinquan Li; Cristiana C. Garcia; Wenchao Feng; Liliya N. Kirpotina; Jonathan Hilmer; Luciana P. Tavares; Arthur W. Layton; Mark T. Quinn; Brian Bothner; Mauro M. Teixeira; Benfang Lei

doi:10.1371/journal.ppat.1002624

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Peer-reviewed

Research Article

Group A Streptococcus Secreted Esterase Hydrolyzes Platelet-Activating Factor to Impede Neutrophil Recruitment and Facilitate Innate Immune Evasion

Mengyao Liu ,

Contributed equally to this work with: Mengyao Liu, Hui Zhu

Affiliation Department of Immunology and Infectious Diseases, Montana State University, Bozeman, Montana, United States of America
⨯
Hui Zhu ,

Contributed equally to this work with: Mengyao Liu, Hui Zhu

Affiliations Department of Immunology and Infectious Diseases, Montana State University, Bozeman, Montana, United States of America, Department of Physiology, Harbin Medical University, Harbin, People's Republic of China
⨯
Jinquan Li,

Affiliations Department of Immunology and Infectious Diseases, Montana State University, Bozeman, Montana, United States of America, State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, People's Republic of China
⨯
Cristiana C. Garcia,

Affiliation Laboratory of Immunopharmacology, Federal University of Minas Gerais, Belo Horizonte, Brazil
⨯
Wenchao Feng,

Affiliation Department of Immunology and Infectious Diseases, Montana State University, Bozeman, Montana, United States of America
⨯
Liliya N. Kirpotina,

Affiliation Department of Immunology and Infectious Diseases, Montana State University, Bozeman, Montana, United States of America
⨯
Jonathan Hilmer,

Affiliation Department of Chemistry and Biochemistry, Montana State University, Bozeman, Montana, United States of America
⨯
Luciana P. Tavares,

Affiliation Laboratory of Immunopharmacology, Federal University of Minas Gerais, Belo Horizonte, Brazil
⨯
Arthur W. Layton,

Affiliation Montana Veterinary Diagnostic Laboratory, Bozeman, Montana, United States of America
⨯
Mark T. Quinn,

Affiliation Department of Immunology and Infectious Diseases, Montana State University, Bozeman, Montana, United States of America
⨯
Brian Bothner,

Affiliation Department of Chemistry and Biochemistry, Montana State University, Bozeman, Montana, United States of America
⨯
Mauro M. Teixeira,

Affiliation Laboratory of Immunopharmacology, Federal University of Minas Gerais, Belo Horizonte, Brazil
⨯
Benfang Lei

* E-mail: blei@montana.edu

Affiliation Department of Immunology and Infectious Diseases, Montana State University, Bozeman, Montana, United States of America
⨯

Group A Streptococcus Secreted Esterase Hydrolyzes Platelet-Activating Factor to Impede Neutrophil Recruitment and Facilitate Innate Immune Evasion

Mengyao Liu,
Hui Zhu,
Jinquan Li,
Cristiana C. Garcia,
Wenchao Feng,
Liliya N. Kirpotina,
Jonathan Hilmer,
Luciana P. Tavares,
Arthur W. Layton,
Mark T. Quinn

Published: April 5, 2012
https://doi.org/10.1371/journal.ppat.1002624

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Hydrolysis
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