Structural Insights into a Unique Legionella pneumophila Effector LidA Recognizing Both GDP and GTP Bound Rab1 in Their Active State

Wei Cheng; Kun Yin; Defen Lu; Bingqing Li; Deyu Zhu; Yuzhen Chen; Hao Zhang; Sujuan Xu; Jijie Chai; Lichuan Gu

doi:10.1371/journal.ppat.1002528

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Peer-reviewed

Research Article

Structural Insights into a Unique Legionella pneumophila Effector LidA Recognizing Both GDP and GTP Bound Rab1 in Their Active State

Wei Cheng ,

Contributed equally to this work with: Wei Cheng, Kun Yin

Affiliation State Key Laboratory of Microbial Technology, Shandong University, Jinan, Shandong, China
⨯
Kun Yin ,

Contributed equally to this work with: Wei Cheng, Kun Yin

Affiliations Key Laboratory for Protein Sciences of Ministry of Education, School of Biological Sciences, Tsinghua University, Beijing, China, Shandong Institute of Parasitical Diseases, Shandong Academy of Medical Sciences, Jining, Shandong, China
⨯
Defen Lu,

Affiliation Key Laboratory for Protein Sciences of Ministry of Education, School of Biological Sciences, Tsinghua University, Beijing, China
⨯
Bingqing Li,

Affiliation Key Laboratory for Protein Sciences of Ministry of Education, School of Biological Sciences, Tsinghua University, Beijing, China
⨯
Deyu Zhu,

Affiliation Key Laboratory for Protein Sciences of Ministry of Education, School of Biological Sciences, Tsinghua University, Beijing, China
⨯
Yuzhen Chen,

Affiliation Shandong Center for Disease Control and Prevention, Jinan, Shandong, China
⨯
Hao Zhang,

Affiliation Key Laboratory for Protein Sciences of Ministry of Education, School of Biological Sciences, Tsinghua University, Beijing, China
⨯
Sujuan Xu,

Affiliation Key Laboratory for Protein Sciences of Ministry of Education, School of Biological Sciences, Tsinghua University, Beijing, China
⨯
Jijie Chai ,

* E-mail: lcgu@sdu.edu.cn (LG); chaijj@mail.tsinghua.edu.cn (JC)

Affiliation State Key Laboratory of Microbial Technology, Shandong University, Jinan, Shandong, China
⨯
Lichuan Gu

* E-mail: lcgu@sdu.edu.cn (LG); chaijj@mail.tsinghua.edu.cn (JC)

Affiliation Key Laboratory for Protein Sciences of Ministry of Education, School of Biological Sciences, Tsinghua University, Beijing, China
⨯

Structural Insights into a Unique Legionella pneumophila Effector LidA Recognizing Both GDP and GTP Bound Rab1 in Their Active State

Wei Cheng,
Kun Yin,
Defen Lu,
Bingqing Li,
Deyu Zhu,
Yuzhen Chen,
Hao Zhang,
Sujuan Xu,
Jijie Chai,
Lichuan Gu

Published: March 1, 2012
https://doi.org/10.1371/journal.ppat.1002528

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