Epstein-Barr Virus Evades CD4+ T Cell Responses in Lytic Cycle through BZLF1-mediated Downregulation of CD74 and the Cooperation of vBcl-2

Open Access

Peer-reviewed

Research Article

Epstein-Barr Virus Evades CD4⁺ T Cell Responses in Lytic Cycle through BZLF1-mediated Downregulation of CD74 and the Cooperation of vBcl-2

Jianmin Zuo,

Affiliation Cancer Research UK Birmingham Cancer Centre, University of Birmingham, Birmingham, United Kingdom
⨯
Wendy A. Thomas,

Affiliation Cancer Research UK Birmingham Cancer Centre, University of Birmingham, Birmingham, United Kingdom
⨯
Tracey A. Haigh,

Affiliation Cancer Research UK Birmingham Cancer Centre, University of Birmingham, Birmingham, United Kingdom
⨯
Leah Fitzsimmons,

Affiliation Cancer Research UK Birmingham Cancer Centre, University of Birmingham, Birmingham, United Kingdom
⨯
Heather M. Long,

Affiliation Cancer Research UK Birmingham Cancer Centre, University of Birmingham, Birmingham, United Kingdom
⨯
Andrew D. Hislop,

Affiliation Cancer Research UK Birmingham Cancer Centre, University of Birmingham, Birmingham, United Kingdom
⨯
Graham S. Taylor,

Affiliation Cancer Research UK Birmingham Cancer Centre, University of Birmingham, Birmingham, United Kingdom
⨯
Martin Rowe

* E-mail: m.rowe@bham.ac.uk

Affiliation Cancer Research UK Birmingham Cancer Centre, University of Birmingham, Birmingham, United Kingdom
⨯

T cells
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Transfection
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Lytic cycle
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Plasmid construction
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Flow cytometry
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Cell staining
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Antigen presentation
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Epstein-Barr virus
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