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Open Access
Peer-reviewed
Research Article
SAMHD1-Deficient CD14+ Cells from Individuals with Aicardi-Goutières Syndrome Are Highly Susceptible to HIV-1 Infection
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André Berger,
Affiliation Division of Medical Biotechnology, Paul-Ehrlich-Institute, Langen, Germany
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Andreas F. R. Sommer ,
Contributed equally to this work with: Andreas F. R. Sommer, Jenny Zwarg
Affiliation Research Group “Host-Pathogen Interactions”, Paul-Ehrlich-Institute, Langen, Germany
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Jenny Zwarg ,
Contributed equally to this work with: Andreas F. R. Sommer, Jenny Zwarg
Affiliation Division of Medical Biotechnology, Paul-Ehrlich-Institute, Langen, Germany
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Matthias Hamdorf,
Affiliation Research Group “Host-Pathogen Interactions”, Paul-Ehrlich-Institute, Langen, Germany
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Karin Welzel,
Affiliation Division of Medical Biotechnology, Paul-Ehrlich-Institute, Langen, Germany
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Nicole Esly,
Affiliation Research Group “Host-Pathogen Interactions”, Paul-Ehrlich-Institute, Langen, Germany
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Sylvia Panitz,
Affiliation Division of Medical Biotechnology, Paul-Ehrlich-Institute, Langen, Germany
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Andreas Reuter,
Affiliation Division of Allergology, Paul-Ehrlich-Institute, Langen, Germany
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Irene Ramos,
Affiliation Department of Microbiology, Mount Sinai School of Medicine, New York, New York, United States of America
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Asavari Jatiani,
Affiliation Department of Microbiology, Mount Sinai School of Medicine, New York, New York, United States of America
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Lubbertus C. F. Mulder,
Affiliation Department of Microbiology, Mount Sinai School of Medicine, New York, New York, United States of America
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Ana Fernandez-Sesma,
Affiliations Department of Microbiology, Mount Sinai School of Medicine, New York, New York, United States of America, The Global Health and Emerging Pathogens Institute, Mount Sinai School of Medicine, New York, New York, United States of America, Division of Infectious Diseases, Department of Medicine, Mount Sinai School of Medicine, New York, New York, United States of America
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Frank Rutsch,
Affiliation Department of General Pediatrics, Münster University Children's Hospital, Münster, Germany
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Viviana Simon,
Affiliations Department of Microbiology, Mount Sinai School of Medicine, New York, New York, United States of America, The Global Health and Emerging Pathogens Institute, Mount Sinai School of Medicine, New York, New York, United States of America, Division of Infectious Diseases, Department of Medicine, Mount Sinai School of Medicine, New York, New York, United States of America
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Renate König ,
* E-mail: renate.koenig@pei.de (RK); egbert.flory@pei.de (EF)
Affiliations Research Group “Host-Pathogen Interactions”, Paul-Ehrlich-Institute, Langen, Germany, Infectious & Inflammatory Disease Center, Sanford-Burnham Medical Research Institute, La Jolla, California, United States of America
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Egbert Flory
* E-mail: renate.koenig@pei.de (RK); egbert.flory@pei.de (EF)
Affiliation Division of Medical Biotechnology, Paul-Ehrlich-Institute, Langen, Germany
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SAMHD1-Deficient CD14+ Cells from Individuals with Aicardi-Goutières Syndrome Are Highly Susceptible to HIV-1 Infection
- André Berger,
- Andreas F. R. Sommer,
- Jenny Zwarg,
- Matthias Hamdorf,
- Karin Welzel,
- Nicole Esly,
- Sylvia Panitz,
- Andreas Reuter,
- Irene Ramos,
- Asavari Jatiani
- Published: December 8, 2011
- https://doi.org/10.1371/journal.ppat.1002425