Early Secreted Antigen ESAT-6 of Mycobacterium tuberculosis Promotes Protective T Helper 17 Cell Responses in a Toll-Like Receptor-2-dependent Manner

Samit Chatterjee; Ved Prakash Dwivedi; Yogesh Singh; Imran Siddiqui; Pawan Sharma; Luc Van Kaer; Debprasad Chattopadhyay; Gobardhan Das

doi:10.1371/journal.ppat.1002378

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Open Access

Peer-reviewed

Research Article

Early Secreted Antigen ESAT-6 of Mycobacterium tuberculosis Promotes Protective T Helper 17 Cell Responses in a Toll-Like Receptor-2-dependent Manner

Samit Chatterjee ,

Contributed equally to this work with: Samit Chatterjee, Ved Prakash Dwivedi

Affiliation Immunology Group, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, India
⨯
Ved Prakash Dwivedi ,

Contributed equally to this work with: Samit Chatterjee, Ved Prakash Dwivedi

Affiliation Immunology Group, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, India
⨯
Yogesh Singh,

Current address: MicroRNA and Lymphocyte Development Research Group, Department of Veterinary Basic Sciences, Royal Veterinary College (University of London), London, United Kingdom

Affiliation Immunology Group, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, India
⨯
Imran Siddiqui,

Affiliation Immunology Group, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, India
⨯
Pawan Sharma,

Affiliation Immunology Group, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, India
⨯
Luc Van Kaer,

Affiliation Department of Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America
⨯
Debprasad Chattopadhyay,

Affiliation ICMR Virus Unit, Calcutta, ID & BG Hospital, GB 4, Beliaghata, Kolkata, India
⨯
Gobardhan Das

* E-mail: dasgo@icgeb.res.in

Affiliation Immunology Group, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, India
⨯

Early Secreted Antigen ESAT-6 of Mycobacterium tuberculosis Promotes Protective T Helper 17 Cell Responses in a Toll-Like Receptor-2-dependent Manner

Samit Chatterjee,
Ved Prakash Dwivedi,
Yogesh Singh,
Imran Siddiqui,
Pawan Sharma,
Luc Van Kaer,
Debprasad Chattopadhyay,
Gobardhan Das

Published: November 10, 2011
https://doi.org/10.1371/journal.ppat.1002378

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Tuberculosis
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Mycobacterium tuberculosis
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Immune response
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Cell differentiation
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