Ultra-Efficient PrP^Sc Amplification Highlights Potentialities and Pitfalls of PMCA Technology

• Gian Mario Cosseddu ,

  * E-mail: gianmario.cosseddu@iss.it

  Affiliations Department of Veterinary Public Health and Food Safety, Istituto Superiore di Sanità, Rome, Italy, Department of Infectology, The SCRIPPS Research Institute, Jupiter, Florida, United States of America

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• Romolo Nonno,

  Affiliation Department of Veterinary Public Health and Food Safety, Istituto Superiore di Sanità, Rome, Italy

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• Gabriele Vaccari,

  Affiliation Department of Veterinary Public Health and Food Safety, Istituto Superiore di Sanità, Rome, Italy

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• Cecilia Bucalossi,

  Affiliation Department of Veterinary Public Health and Food Safety, Istituto Superiore di Sanità, Rome, Italy

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• Natalia Fernandez-Borges,

  Affiliations Department of Infectology, The SCRIPPS Research Institute, Jupiter, Florida, United States of America, 33458CIC bioGUNE, Parque Tecnológico de Bizkaia, Derio, Spain

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• Michele Angelo Di Bari,

  Affiliation Department of Veterinary Public Health and Food Safety, Istituto Superiore di Sanità, Rome, Italy

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• Joaquin Castilla,

  Affiliations Department of Infectology, The SCRIPPS Research Institute, Jupiter, Florida, United States of America, 33458CIC bioGUNE, Parque Tecnológico de Bizkaia, Derio, Spain, IKERBASQUE, Basque Foundation for Science, Bilbao, Spain

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• Umberto Agrimi

  Affiliation Department of Veterinary Public Health and Food Safety, Istituto Superiore di Sanità, Rome, Italy

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