Sequence-Based Analysis Uncovers an Abundance of Non-Coding RNA in the Total Transcriptome of Mycobacterium tuberculosis

Kristine B. Arnvig; Iñaki Comas; Nicholas R. Thomson; Joanna Houghton; Helena I. Boshoff; Nicholas J. Croucher; Graham Rose; Timothy T. Perkins; Julian Parkhill; Gordon Dougan; Douglas B. Young

doi:10.1371/journal.ppat.1002342

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Open Access

Peer-reviewed

Research Article

Sequence-Based Analysis Uncovers an Abundance of Non-Coding RNA in the Total Transcriptome of Mycobacterium tuberculosis

Kristine B. Arnvig ,

* E-mail: karnvig@nimr.mrc.ac.uk

Affiliation Division of Mycobacterial Research, MRC National Institute for Medical Research, London, United Kingdom
⨯
Iñaki Comas,

Current address: Genomics and Health Unit, Centre for Public Health Research, Valencia, Spain

Affiliation Division of Mycobacterial Research, MRC National Institute for Medical Research, London, United Kingdom
⨯
Nicholas R. Thomson,

Affiliation The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, United Kingdom
⨯
Joanna Houghton,

Affiliation Division of Mycobacterial Research, MRC National Institute for Medical Research, London, United Kingdom
⨯
Helena I. Boshoff,

Affiliation NIAID, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Nicholas J. Croucher,

Affiliation The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, United Kingdom
⨯
Graham Rose,

Affiliation Division of Mycobacterial Research, MRC National Institute for Medical Research, London, United Kingdom
⨯
Timothy T. Perkins,

Affiliation The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, United Kingdom
⨯
Julian Parkhill,

Affiliation The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, United Kingdom
⨯
Gordon Dougan,

Affiliation The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, United Kingdom
⨯
Douglas B. Young

Affiliation Division of Mycobacterial Research, MRC National Institute for Medical Research, London, United Kingdom
⨯

Sequence-Based Analysis Uncovers an Abundance of Non-Coding RNA in the Total Transcriptome of Mycobacterium tuberculosis

Kristine B. Arnvig,
Iñaki Comas,
Nicholas R. Thomson,
Joanna Houghton,
Helena I. Boshoff,
Nicholas J. Croucher,
Graham Rose,
Timothy T. Perkins,
Julian Parkhill,
Gordon Dougan

Published: November 3, 2011
https://doi.org/10.1371/journal.ppat.1002342

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Mycobacterium tuberculosis
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Transcriptome analysis
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Gene expression
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RNA sequencing
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Messenger RNA
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5' UTR
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Ribosomal RNA
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DNA transcription
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