Helicobacter pylori Exploits a Unique Repertoire of Type IV Secretion System Components for Pilus Assembly at the Bacteria-Host Cell Interface

Carrie L. Shaffer; Jennifer A. Gaddy; John T. Loh; Elizabeth M. Johnson; Salisha Hill; Ewa E. Hennig; Mark S. McClain; W. Hayes McDonald; Timothy L. Cover

doi:10.1371/journal.ppat.1002237

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Peer-reviewed

Research Article

Helicobacter pylori Exploits a Unique Repertoire of Type IV Secretion System Components for Pilus Assembly at the Bacteria-Host Cell Interface

Carrie L. Shaffer,

Affiliation Department of Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America
⨯
Jennifer A. Gaddy,

Affiliation Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America
⨯
John T. Loh,

Affiliation Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America
⨯
Elizabeth M. Johnson,

Affiliation Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America
⨯
Salisha Hill,

Affiliation Proteomics Laboratory, Mass Spectrometry Research Center, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America
⨯
Ewa E. Hennig,

Affiliation Department of Gastroenterology and Hepatology, Medical Center for Postgraduate Education, and Department of Oncological Genetics, Cancer Center Institute, Warsaw, Poland
⨯
Mark S. McClain,

Affiliation Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America
⨯
W. Hayes McDonald,

Affiliation Proteomics Laboratory, Mass Spectrometry Research Center, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America
⨯
Timothy L. Cover

* E-mail: timothy.l.cover@vanderbilt.edu

Affiliations Department of Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America, Veterans Affairs Tennessee Valley Healthcare System, Nashville, Tennessee, United States of America
⨯

Helicobacter pylori Exploits a Unique Repertoire of Type IV Secretion System Components for Pilus Assembly at the Bacteria-Host Cell Interface

Carrie L. Shaffer,
Jennifer A. Gaddy,
John T. Loh,
Elizabeth M. Johnson,
Salisha Hill,
Ewa E. Hennig,
Mark S. McClain,
W. Hayes McDonald,
Timothy L. Cover

Published: September 1, 2011
https://doi.org/10.1371/journal.ppat.1002237

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Helicobacter pylori
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Pili and fimbriae
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Mutant strains
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Epithelial cells
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Secretion systems
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Immune serum
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