The SV40 Late Protein VP4 Is a Viroporin that Forms Pores to Disrupt Membranes for Viral Release

Open Access

Peer-reviewed

Research Article

Smita Raghava,

Affiliation Department of Biochemistry and Molecular Biology, Program in Molecular and Cellular Biology, University of Massachusetts, Amherst, Massachusetts, United States of America
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Kristina M. Giorda,

Affiliation Department of Biochemistry and Molecular Biology, Program in Molecular and Cellular Biology, University of Massachusetts, Amherst, Massachusetts, United States of America
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Fabian B. Romano,

Affiliation Department of Biochemistry and Molecular Biology, Program in Molecular and Cellular Biology, University of Massachusetts, Amherst, Massachusetts, United States of America
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Alejandro P. Heuck,

Affiliation Department of Biochemistry and Molecular Biology, Program in Molecular and Cellular Biology, University of Massachusetts, Amherst, Massachusetts, United States of America
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Daniel N. Hebert

* E-mail: dhebert@biochem.umass.edu

Affiliation Department of Biochemistry and Molecular Biology, Program in Molecular and Cellular Biology, University of Massachusetts, Amherst, Massachusetts, United States of America
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Cell membranes
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Liposomes
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Partial disruption of cell membrane
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Membrane proteins
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Lipids
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Membrane characteristics
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SV40
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Lysis (medicine)
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