Highly Pathogenic Avian Influenza Virus H5N1 Infects Alveolar Macrophages without Virus Production or Excessive TNF-Alpha Induction

Open Access

Peer-reviewed

Research Article

Debby van Riel,

Affiliation Department of Virology, Erasmus MC, Rotterdam, The Netherlands
⨯
Lonneke M. E. Leijten,

Affiliation Department of Virology, Erasmus MC, Rotterdam, The Netherlands
⨯
Menno van der Eerden,

Affiliation Department of Pulmonary Medicine, Erasmus MC, Rotterdam, The Netherlands
⨯
Henk C. Hoogsteden,

Affiliation Department of Pulmonary Medicine, Erasmus MC, Rotterdam, The Netherlands
⨯
Leonie A. Boven,

Affiliations Department of Immunology, Erasmus MC, Rotterdam, The Netherlands, Department of Clinical Chemistry, Meander MC, Amersfoort, The Netherlands
⨯
Bart N. Lambrecht,

Affiliation Laboratory of Immunoregulation and Mucosal Immunology, University of Ghent, Ghent, Belgium
⨯
Albert D. M. E. Osterhaus,

Affiliation Department of Virology, Erasmus MC, Rotterdam, The Netherlands
⨯
Thijs Kuiken

* E-mail: t.kuiken@erasmusmc.nl

Affiliation Department of Virology, Erasmus MC, Rotterdam, The Netherlands
⨯

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H5N1
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Alveolar macrophages
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Influenza viruses
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Respiratory infections
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Monocytes
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Macrophages
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Biopsy
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H1N1
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