Crystal Structure and Functional Analysis of the SARS-Coronavirus RNA Cap 2′-O-Methyltransferase nsp10/nsp16 Complex

Etienne Decroly; Claire Debarnot; François Ferron; Mickael Bouvet; Bruno Coutard; Isabelle Imbert; Laure Gluais; Nicolas Papageorgiou; Andrew Sharff; Gérard Bricogne; Miguel Ortiz-Lombardia; Julien Lescar; Bruno Canard

doi:10.1371/journal.ppat.1002059

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Open Access

Peer-reviewed

Research Article

Crystal Structure and Functional Analysis of the SARS-Coronavirus RNA Cap 2′-O-Methyltransferase nsp10/nsp16 Complex

Etienne Decroly ,

* E-mail: etienne.decroly@afmb.univ-mrs.fr (ED); bruno.canard@afmb.univ-mrs.fr (BC)

Affiliation Centre National de la Recherche Scientifique and Université de la Méditerranée, UMR 6098, Architecture et Fonction des Macromolécules Biologiques, Marseille, France
⨯
Claire Debarnot,

Affiliation Centre National de la Recherche Scientifique and Université de la Méditerranée, UMR 6098, Architecture et Fonction des Macromolécules Biologiques, Marseille, France
⨯
François Ferron,

Affiliation Centre National de la Recherche Scientifique and Université de la Méditerranée, UMR 6098, Architecture et Fonction des Macromolécules Biologiques, Marseille, France
⨯
Mickael Bouvet,

Affiliation Centre National de la Recherche Scientifique and Université de la Méditerranée, UMR 6098, Architecture et Fonction des Macromolécules Biologiques, Marseille, France
⨯
Bruno Coutard,

Affiliation Centre National de la Recherche Scientifique and Université de la Méditerranée, UMR 6098, Architecture et Fonction des Macromolécules Biologiques, Marseille, France
⨯
Isabelle Imbert,

Affiliation Centre National de la Recherche Scientifique and Université de la Méditerranée, UMR 6098, Architecture et Fonction des Macromolécules Biologiques, Marseille, France
⨯
Laure Gluais,

Affiliation Centre National de la Recherche Scientifique and Université de la Méditerranée, UMR 6098, Architecture et Fonction des Macromolécules Biologiques, Marseille, France
⨯
Nicolas Papageorgiou,

Affiliation Centre National de la Recherche Scientifique and Université de la Méditerranée, UMR 6098, Architecture et Fonction des Macromolécules Biologiques, Marseille, France
⨯
Andrew Sharff,

Affiliation Global Phasing Ltd., Sheraton House, Castle Park, Cambridge, United Kingdom
⨯
Gérard Bricogne,

Affiliation Global Phasing Ltd., Sheraton House, Castle Park, Cambridge, United Kingdom
⨯
Miguel Ortiz-Lombardia,

Affiliation Centre National de la Recherche Scientifique and Université de la Méditerranée, UMR 6098, Architecture et Fonction des Macromolécules Biologiques, Marseille, France
⨯
Julien Lescar,

Affiliations Centre National de la Recherche Scientifique and Université de la Méditerranée, UMR 6098, Architecture et Fonction des Macromolécules Biologiques, Marseille, France, School of Biological Sciences, Nanyang Technological University, Singapore, Republic of Singapore
⨯
Bruno Canard

* E-mail: etienne.decroly@afmb.univ-mrs.fr (ED); bruno.canard@afmb.univ-mrs.fr (BC)

Affiliation Centre National de la Recherche Scientifique and Université de la Méditerranée, UMR 6098, Architecture et Fonction des Macromolécules Biologiques, Marseille, France
⨯

Crystal Structure and Functional Analysis of the SARS-Coronavirus RNA Cap 2′-O-Methyltransferase nsp10/nsp16 Complex

Etienne Decroly,
Claire Debarnot,
François Ferron,
Mickael Bouvet,
Bruno Coutard,
Isabelle Imbert,
Laure Gluais,
Nicolas Papageorgiou,
Andrew Sharff,
Gérard Bricogne

Published: May 26, 2011
https://doi.org/10.1371/journal.ppat.1002059

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