An E2F1-Mediated DNA Damage Response Contributes to the Replication of Human Cytomegalovirus

Xiaofei E; Mary T. Pickering; Michelle Debatis; Jonathan Castillo; Alexander Lagadinos; Shixia Wang; Shan Lu; Timothy F. Kowalik

doi:10.1371/journal.ppat.1001342

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Open Access

Peer-reviewed

Research Article

An E2F1-Mediated DNA Damage Response Contributes to the Replication of Human Cytomegalovirus

Xiaofei E ,

Contributed equally to this work with: Xiaofei E, Mary T. Pickering

Affiliations Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America, Program in Immunology and Virology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
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Mary T. Pickering ,

Contributed equally to this work with: Xiaofei E, Mary T. Pickering

Affiliation Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
⨯
Michelle Debatis,

Affiliation Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
⨯
Jonathan Castillo,

Affiliations Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America, Program in Immunology and Virology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
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Alexander Lagadinos,

Affiliations Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America, Program in Immunology and Virology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
⨯
Shixia Wang,

Affiliations Program in Immunology and Virology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America, Laboratory of Nucleic Acid Vaccines, Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
⨯
Shan Lu,

Affiliations Program in Immunology and Virology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America, Laboratory of Nucleic Acid Vaccines, Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
⨯
Timothy F. Kowalik

* E-mail: timothy.kowalik@umassmed.edu

Affiliations Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America, Program in Immunology and Virology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
⨯

An E2F1-Mediated DNA Damage Response Contributes to the Replication of Human Cytomegalovirus

Xiaofei E,
Mary T. Pickering,
Michelle Debatis,
Jonathan Castillo,
Alexander Lagadinos,
Shixia Wang,
Shan Lu,
Timothy F. Kowalik

Published: May 12, 2011
https://doi.org/10.1371/journal.ppat.1001342

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Viral replication
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Fibroblasts
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Small interfering RNA
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DNA damage
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Human cytomegalovirus
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