Pathogen Specific, IRF3-Dependent Signaling and Innate Resistance to Human Kidney Infection

Hans Fischer; Nataliya Lutay; Bryndís Ragnarsdóttir; Manisha Yadav; Klas Jönsson; Alexander Urbano; Ahmed Al Hadad; Sebastian Rämisch; Petter Storm; Ulrich Dobrindt; Ellaine Salvador; Diana Karpman; Ulf Jodal; Catharina Svanborg

doi:10.1371/journal.ppat.1001109

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Open Access

Peer-reviewed

Research Article

Pathogen Specific, IRF3-Dependent Signaling and Innate Resistance to Human Kidney Infection

Hans Fischer,

Affiliation Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, Lund, Sweden
⨯
Nataliya Lutay,

Affiliation Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, Lund, Sweden
⨯
Bryndís Ragnarsdóttir,

Affiliation Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, Lund, Sweden
⨯
Manisha Yadav,

Affiliation Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, Lund, Sweden
⨯
Klas Jönsson,

Affiliation Singapore Immunology Network (SIgN), Biomedical Sciences Institutes, Agency for Science, Technology, and Research (A*STAR), Immunos, BIOPOLIS, Singapore, Singapore
⨯
Alexander Urbano,

Affiliation Singapore Immunology Network (SIgN), Biomedical Sciences Institutes, Agency for Science, Technology, and Research (A*STAR), Immunos, BIOPOLIS, Singapore, Singapore
⨯
Ahmed Al Hadad,

Affiliation Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, Lund, Sweden
⨯
Sebastian Rämisch,

Affiliation Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, Lund, Sweden
⨯
Petter Storm,

Affiliation Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, Lund, Sweden
⨯
Ulrich Dobrindt,

Affiliation Institute for Molecular Biology of Infectious Diseases, Julius-Maximilians-University Würzburg, Würzburg, Germany
⨯
Ellaine Salvador,

Affiliation Institute for Molecular Biology of Infectious Diseases, Julius-Maximilians-University Würzburg, Würzburg, Germany
⨯
Diana Karpman,

Affiliation Department of Pediatrics, Clinical Sciences Lund, Lund University, and Lund University Hospital, Lund, Sweden
⨯
Ulf Jodal,

Affiliation Pediatric-Uronephrology Center, Queen Silvia Children's Hospital, University of Gothenburg, Sweden
⨯
Catharina Svanborg

* E-mail: Catharina.Svanborg@med.lu.se

Affiliations Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, Lund, Sweden, Singapore Immunology Network (SIgN), Biomedical Sciences Institutes, Agency for Science, Technology, and Research (A*STAR), Immunos, BIOPOLIS, Singapore, Singapore
⨯

Pathogen Specific, IRF3-Dependent Signaling and Innate Resistance to Human Kidney Infection

Hans Fischer,
Nataliya Lutay,
Bryndís Ragnarsdóttir,
Manisha Yadav,
Klas Jönsson,
Alexander Urbano,
Ahmed Al Hadad,
Sebastian Rämisch,
Petter Storm,
Ulrich Dobrindt

Published: September 23, 2010
https://doi.org/10.1371/journal.ppat.1001109

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Bacterial pathogens
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Phosphorylation
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Kidneys
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Immune receptor signaling
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Small interfering RNA
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Urinary tract infections
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