Enterohemorrhagic E. coli Requires N-WASP for Efficient Type III Translocation but Not for EspFU-Mediated Actin Pedestal Formation

Didier Vingadassalom; Kenneth G. Campellone; Michael J. Brady; Brian Skehan; Scott E. Battle; Douglas Robbins; Archana Kapoor; Gail Hecht; Scott B. Snapper; John M. Leong

doi:10.1371/journal.ppat.1001056

Loading metrics

Open Access

Peer-reviewed

Research Article

Enterohemorrhagic E. coli Requires N-WASP for Efficient Type III Translocation but Not for EspF_U-Mediated Actin Pedestal Formation

Didier Vingadassalom ,

Contributed equally to this work with: Didier Vingadassalom, Kenneth G. Campellone

Affiliation Department of Molecular Genetics and Microbiology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
⨯
Kenneth G. Campellone ,

Contributed equally to this work with: Didier Vingadassalom, Kenneth G. Campellone

Current address: Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, California, United States of America

Affiliation Department of Molecular Genetics and Microbiology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
⨯
Michael J. Brady,

Affiliation Department of Molecular Genetics and Microbiology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
⨯
Brian Skehan,

Affiliation Department of Molecular Genetics and Microbiology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
⨯
Scott E. Battle,

Affiliation Section of Digestive Diseases and Nutrition, University of Illinois at Chicago, Chicago, Illinois, United States of America
⨯
Douglas Robbins,

Affiliation Department of Molecular Genetics and Microbiology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
⨯
Archana Kapoor,

Affiliation Department of Medicine and Immunology, Massachusetts General Hospital, Boston, Massachusetts, United States of America
⨯
Gail Hecht,

Affiliation Section of Digestive Diseases and Nutrition, University of Illinois at Chicago, Chicago, Illinois, United States of America
⨯
Scott B. Snapper,

Affiliation Department of Medicine and Immunology, Massachusetts General Hospital, Boston, Massachusetts, United States of America
⨯
John M. Leong

* E-mail: John.Leong@umassmed.edu

Affiliation Department of Molecular Genetics and Microbiology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
⨯

Enterohemorrhagic E. coli Requires N-WASP for Efficient Type III Translocation but Not for EspF_U-Mediated Actin Pedestal Formation

Didier Vingadassalom,
Kenneth G. Campellone,
Michael J. Brady,
Brian Skehan,
Scott E. Battle,
Douglas Robbins,
Archana Kapoor,
Gail Hecht,
Scott B. Snapper,
John M. Leong

Published: August 19, 2010
https://doi.org/10.1371/journal.ppat.1001056

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Actins
Is the Subject Area "Actins" applicable to this article?

Thanks for your feedback.
Cell fusion
Is the Subject Area "Cell fusion" applicable to this article?

Thanks for your feedback.
Enterohaemorrhagic Escherichia coli
Is the Subject Area "Enterohaemorrhagic Escherichia coli" applicable to this article?

Thanks for your feedback.
Actin polymerization
Is the Subject Area "Actin polymerization" applicable to this article?

Thanks for your feedback.
Cell membranes
Is the Subject Area "Cell membranes" applicable to this article?

Thanks for your feedback.
Cell staining
Is the Subject Area "Cell staining" applicable to this article?

Thanks for your feedback.
DAPI staining
Is the Subject Area "DAPI staining" applicable to this article?

Thanks for your feedback.
Membrane proteins
Is the Subject Area "Membrane proteins" applicable to this article?

Thanks for your feedback.