Tip-DC Development during Parasitic Infection Is Regulated by IL-10 and Requires CCL2/CCR2, IFN-γ and MyD88 Signaling

Tom Bosschaerts; Martin Guilliams; Benoît Stijlemans; Yannick Morias; Daniel Engel; Frank Tacke; Michel Hérin; Patrick De Baetselier; Alain Beschin

doi:10.1371/journal.ppat.1001045

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Peer-reviewed

Research Article

Tip-DC Development during Parasitic Infection Is Regulated by IL-10 and Requires CCL2/CCR2, IFN-γ and MyD88 Signaling

Tom Bosschaerts,

Affiliations Department of Molecular and Cellular Interactions, VIB, Brussels, Belgium, Laboratory of Cellular and Molecular Immunology, Vrije Universiteit Brussel, Brussels, Belgium
⨯
Martin Guilliams,

Affiliations Department of Molecular and Cellular Interactions, VIB, Brussels, Belgium, Laboratory of Cellular and Molecular Immunology, Vrije Universiteit Brussel, Brussels, Belgium
⨯
Benoît Stijlemans,

Affiliations Department of Molecular and Cellular Interactions, VIB, Brussels, Belgium, Laboratory of Cellular and Molecular Immunology, Vrije Universiteit Brussel, Brussels, Belgium
⨯
Yannick Morias,

Affiliations Department of Molecular and Cellular Interactions, VIB, Brussels, Belgium, Laboratory of Cellular and Molecular Immunology, Vrije Universiteit Brussel, Brussels, Belgium
⨯
Daniel Engel,

Affiliation Institute for Molecular Medicine and Experimental Immunology, University Clinic of Bonn, Bonn, Germany
⨯
Frank Tacke,

Affiliation Department of Medicine III, RWTH-University Hospital Aachen, Aachen, Germany
⨯
Michel Hérin,

Affiliation Cell and Tissue Laboratory, Unité de Recherche en Physiologie Moléculaire, Facultés Universitaires Notre-Dame de la Paix, Namur, Belgium
⨯
Patrick De Baetselier,

Affiliations Department of Molecular and Cellular Interactions, VIB, Brussels, Belgium, Laboratory of Cellular and Molecular Immunology, Vrije Universiteit Brussel, Brussels, Belgium
⨯
Alain Beschin

* E-mail: abeschin@vub.ac.be

Affiliations Department of Molecular and Cellular Interactions, VIB, Brussels, Belgium, Laboratory of Cellular and Molecular Immunology, Vrije Universiteit Brussel, Brussels, Belgium
⨯

Tip-DC Development during Parasitic Infection Is Regulated by IL-10 and Requires CCL2/CCR2, IFN-γ and MyD88 Signaling

Tom Bosschaerts,
Martin Guilliams,
Benoît Stijlemans,
Yannick Morias,
Daniel Engel,
Frank Tacke,
Michel Hérin,
Patrick De Baetselier,
Alain Beschin

Published: August 12, 2010
https://doi.org/10.1371/journal.ppat.1001045

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