NleG Type 3 Effectors from Enterohaemorrhagic Escherichia coli Are U-Box E3 Ubiquitin Ligases

• Bin Wu ,

  Contributed equally to this work with: Bin Wu, Tatiana Skarina

  Affiliations Division of Cancer Genomics and Proteomics, Ontario Cancer Institute, Toronto, Ontario, Canada, Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada

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• Tatiana Skarina ,

  Contributed equally to this work with: Bin Wu, Tatiana Skarina

  Affiliation Banting and Best Department for Medical Research, University of Toronto, C.H. Best Institute, Toronto, Ontario, Canada

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• Adelinda Yee,

  Affiliations Division of Cancer Genomics and Proteomics, Ontario Cancer Institute, Toronto, Ontario, Canada, Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada

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• Marie-Claude Jobin,

  Affiliations Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada, Banting and Best Department for Medical Research, University of Toronto, C.H. Best Institute, Toronto, Ontario, Canada

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• Rosa DiLeo,

  Affiliation Banting and Best Department for Medical Research, University of Toronto, C.H. Best Institute, Toronto, Ontario, Canada

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• Anthony Semesi,

  Affiliations Division of Cancer Genomics and Proteomics, Ontario Cancer Institute, Toronto, Ontario, Canada, Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada

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• Christophe Fares,

  Affiliations Division of Cancer Genomics and Proteomics, Ontario Cancer Institute, Toronto, Ontario, Canada, Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada

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• Alexander Lemak,

  Affiliations Division of Cancer Genomics and Proteomics, Ontario Cancer Institute, Toronto, Ontario, Canada, Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada

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• Brian K. Coombes,

  Affiliation Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada

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• Cheryl H. Arrowsmith,

  Affiliations Division of Cancer Genomics and Proteomics, Ontario Cancer Institute, Toronto, Ontario, Canada, Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada, Banting and Best Department for Medical Research, University of Toronto, C.H. Best Institute, Toronto, Ontario, Canada

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• Alexander U. Singer,

  Affiliations Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada, Banting and Best Department for Medical Research, University of Toronto, C.H. Best Institute, Toronto, Ontario, Canada

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• Alexei Savchenko

  * E-mail: alexei.savchenko@utoronto.ca

  Affiliations Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada, Banting and Best Department for Medical Research, University of Toronto, C.H. Best Institute, Toronto, Ontario, Canada

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