Muc2 Protects against Lethal Infectious Colitis by Disassociating Pathogenic and Commensal Bacteria from the Colonic Mucosa

Kirk S. B. Bergstrom; Vanessa Kissoon-Singh; Deanna L. Gibson; Caixia Ma; Marinieve Montero; Ho Pan Sham; Natasha Ryz; Tina Huang; Anna Velcich; B. Brett Finlay; Kris Chadee; Bruce A. Vallance

doi:10.1371/journal.ppat.1000902

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Open Access

Peer-reviewed

Research Article

Muc2 Protects against Lethal Infectious Colitis by Disassociating Pathogenic and Commensal Bacteria from the Colonic Mucosa

Kirk S. B. Bergstrom,

Affiliation Department of Pediatrics, Division of Gastroenterology, Child and Family Research Institute, Vancouver, British Columbia, Canada
⨯
Vanessa Kissoon-Singh,

Affiliation Department of Microbiology and Infectious Diseases, University of Calgary, Calgary, Alberta, Canada
⨯
Deanna L. Gibson,

Affiliation Department of Biology and Physical Geography, Irving K. Barber School of Arts and Sciences, University of British Columbia-Okanagan, Kelowna, British Columbia, Canada
⨯
Caixia Ma,

Affiliation Department of Pediatrics, Division of Gastroenterology, Child and Family Research Institute, Vancouver, British Columbia, Canada
⨯
Marinieve Montero,

Affiliation Department of Pediatrics, Division of Gastroenterology, Child and Family Research Institute, Vancouver, British Columbia, Canada
⨯
Ho Pan Sham,

Affiliation Department of Pediatrics, Division of Gastroenterology, Child and Family Research Institute, Vancouver, British Columbia, Canada
⨯
Natasha Ryz,

Affiliation Department of Pediatrics, Division of Gastroenterology, Child and Family Research Institute, Vancouver, British Columbia, Canada
⨯
Tina Huang,

Affiliation Department of Pediatrics, Division of Gastroenterology, Child and Family Research Institute, Vancouver, British Columbia, Canada
⨯
Anna Velcich,

Affiliation Department of Oncology, Albert Einstein Cancer Center/Montefiore Medical Center, Bronx, New York, United States of America
⨯
B. Brett Finlay,

Affiliation Michael Smith Laboratories and Department of Microbiology and Immunology, University of British Columbia, Vancouver, British Columbia, Canada
⨯
Kris Chadee ,

* E-mail: kchadee@ucalgary.ca (KC); bvallance@cw.bc.ca (BAV)

Affiliation Department of Microbiology and Infectious Diseases, University of Calgary, Calgary, Alberta, Canada
⨯
Bruce A. Vallance

* E-mail: kchadee@ucalgary.ca (KC); bvallance@cw.bc.ca (BAV)

Affiliation Department of Pediatrics, Division of Gastroenterology, Child and Family Research Institute, Vancouver, British Columbia, Canada
⨯

Muc2 Protects against Lethal Infectious Colitis by Disassociating Pathogenic and Commensal Bacteria from the Colonic Mucosa

Kirk S. B. Bergstrom,
Vanessa Kissoon-Singh,
Deanna L. Gibson,
Caixia Ma,
Marinieve Montero,
Ho Pan Sham,
Natasha Ryz,
Tina Huang,
Anna Velcich,
B. Brett Finlay

Published: May 13, 2010
https://doi.org/10.1371/journal.ppat.1000902

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