Antagonism of Tetherin Restriction of HIV-1 Release by Vpu Involves Binding and Sequestration of the Restriction Factor in a Perinuclear Compartment

Open Access

Peer-reviewed

Research Article

Mathieu Dubé,

Affiliation Laboratory of Human Retrovirology, Institut de recherches cliniques de Montréal (IRCM), Montreal, Quebec, Canada
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Bibhuti Bhusan Roy,

Affiliation Laboratory of Human Retrovirology, Institut de recherches cliniques de Montréal (IRCM), Montreal, Quebec, Canada
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Pierre Guiot-Guillain,

Affiliation Laboratory of Human Retrovirology, Institut de recherches cliniques de Montréal (IRCM), Montreal, Quebec, Canada
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Julie Binette,

Affiliation Laboratory of Human Retrovirology, Institut de recherches cliniques de Montréal (IRCM), Montreal, Quebec, Canada
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Johanne Mercier,

Affiliation Laboratory of Human Retrovirology, Institut de recherches cliniques de Montréal (IRCM), Montreal, Quebec, Canada
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Antoine Chiasson,

Affiliation Laboratory of Human Retrovirology, Institut de recherches cliniques de Montréal (IRCM), Montreal, Quebec, Canada
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Éric A. Cohen

* E-mail: eric.cohen@ircm.qc.ca

Affiliations Laboratory of Human Retrovirology, Institut de recherches cliniques de Montréal (IRCM), Montreal, Quebec, Canada, Department of Microbiology and Immunology, Université de Montréal, Montreal, Quebec, Canada
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HIV-1
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Transfection
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HeLa cells
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293T cells
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Cell membranes
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Plasmid construction
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Endocytosis
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Membrane proteins
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