Dynamic Imaging of Experimental Leishmania donovani-Induced Hepatic Granulomas Detects Kupffer Cell-Restricted Antigen Presentation to Antigen-Specific CD8+ T Cells

Open Access

Peer-reviewed

Research Article

Dynamic Imaging of Experimental Leishmania donovani-Induced Hepatic Granulomas Detects Kupffer Cell-Restricted Antigen Presentation to Antigen-Specific CD8⁺ T Cells

Lynette Beattie,

Affiliation Centre for Immunology and Infection, Hull York Medical School and Department of Biology, University of York, York, United Kingdom
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Adam Peltan,

Affiliation Centre for Immunology and Infection, Hull York Medical School and Department of Biology, University of York, York, United Kingdom
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Asher Maroof,

Affiliation Centre for Immunology and Infection, Hull York Medical School and Department of Biology, University of York, York, United Kingdom
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Alun Kirby,

Affiliation Centre for Immunology and Infection, Hull York Medical School and Department of Biology, University of York, York, United Kingdom
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Najmeeyah Brown,

Affiliation Centre for Immunology and Infection, Hull York Medical School and Department of Biology, University of York, York, United Kingdom
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Mark Coles,

Affiliation Centre for Immunology and Infection, Hull York Medical School and Department of Biology, University of York, York, United Kingdom
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Deborah F. Smith,

Affiliation Centre for Immunology and Infection, Hull York Medical School and Department of Biology, University of York, York, United Kingdom
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Paul M. Kaye

* E-mail: pmk2@york.ac.uk

Affiliation Centre for Immunology and Infection, Hull York Medical School and Department of Biology, University of York, York, United Kingdom
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Granulomas
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T cells
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Leishmania donovani
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Cytotoxic T cells
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Parasitic diseases
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Amastigotes
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Macrophages
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Antigen presentation
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