Direct Visualization by Cryo-EM of the Mycobacterial Capsular Layer: A Labile Structure Containing ESX-1-Secreted Proteins

• Musa Sani ,

  Contributed equally to this work with: Musa Sani, Edith N. G. Houben, Jeroen Geurtsen

  Affiliation Division of Cell Biology-B6, Netherlands Cancer Institute–Antoni van Leeuwenhoek Hospital (NKI-AVL), Amsterdam, the Netherlands

  ⨯
• Edith N. G. Houben ,

  Contributed equally to this work with: Musa Sani, Edith N. G. Houben, Jeroen Geurtsen

  Affiliation Department of Medical Microbiology and Infection Control, VU University Medical Centre, Amsterdam, the Netherlands

  ⨯
• Jeroen Geurtsen ,

  Contributed equally to this work with: Musa Sani, Edith N. G. Houben, Jeroen Geurtsen

  Affiliation Department of Medical Microbiology and Infection Control, VU University Medical Centre, Amsterdam, the Netherlands

  ⨯
• Jason Pierson,

  Affiliation Division of Cell Biology-B6, Netherlands Cancer Institute–Antoni van Leeuwenhoek Hospital (NKI-AVL), Amsterdam, the Netherlands

  ⨯
• Karin de Punder,

  Affiliation Division of Cell Biology-B6, Netherlands Cancer Institute–Antoni van Leeuwenhoek Hospital (NKI-AVL), Amsterdam, the Netherlands

  ⨯
• Maaike van Zon,

  Affiliation Division of Cell Biology-B6, Netherlands Cancer Institute–Antoni van Leeuwenhoek Hospital (NKI-AVL), Amsterdam, the Netherlands

  ⨯
• Brigitte Wever,

  Affiliation Department of Medical Microbiology and Infection Control, VU University Medical Centre, Amsterdam, the Netherlands

  ⨯
• Sander R. Piersma,

  Affiliation Department of Medical Oncology, VU University Medical Centre, Amsterdam, the Netherlands

  ⨯
• Connie R. Jiménez,

  Affiliation Department of Medical Oncology, VU University Medical Centre, Amsterdam, the Netherlands

  ⨯
• Mamadou Daffé,

  Current address: Université de Toulouse (Toulouse III), Toulouse, France

  Affiliation CNRS, Institut de Pharmacologie et de Biologie Structurale, Département Mécanismes Moléculaires des Infections Mycobactériennes, Toulouse, France

  ⨯
• Ben J. Appelmelk,

  Affiliation Department of Medical Microbiology and Infection Control, VU University Medical Centre, Amsterdam, the Netherlands

  ⨯
• Wilbert Bitter,

  Affiliation Department of Medical Microbiology and Infection Control, VU University Medical Centre, Amsterdam, the Netherlands

  ⨯
• Nicole van der Wel ,

  * E-mail: n.vd.wel@nki.nl (NvdW); p.peters@nki.nl (PJP)

  Affiliation Division of Cell Biology-B6, Netherlands Cancer Institute–Antoni van Leeuwenhoek Hospital (NKI-AVL), Amsterdam, the Netherlands

  ⨯
• Peter J. Peters

  * E-mail: n.vd.wel@nki.nl (NvdW); p.peters@nki.nl (PJP)

  Affiliations Division of Cell Biology-B6, Netherlands Cancer Institute–Antoni van Leeuwenhoek Hospital (NKI-AVL), Amsterdam, the Netherlands, Kavli Institute of Nanoscience, Delft University of Technology, Delft, the Netherlands

  ⨯