Evolutionary Trajectories of Beta-Lactamase CTX-M-1 Cluster Enzymes: Predicting Antibiotic Resistance

Ângela Novais; Iñaki Comas; Fernando Baquero; Rafael Cantón; Teresa M. Coque; Andrés Moya; Fernando González-Candelas; Juan-Carlos Galán

doi:10.1371/journal.ppat.1000735

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Research Article

Evolutionary Trajectories of Beta-Lactamase CTX-M-1 Cluster Enzymes: Predicting Antibiotic Resistance

Ângela Novais,

Affiliations Hospital Universitario Ramón y Cajal, IMSALUD, Madrid, Spain, CIBER en Epidemiología y Salud Pública (CIBERESP), Madrid, Spain
⨯
Iñaki Comas,

Affiliations Unidad Mixta Genómica y Salud CSISP/UV-Instituto Cavanilles, Valencia, Spain, MRC National Institute for Medical Research, London, United Kingdom
⨯
Fernando Baquero,

Affiliations Hospital Universitario Ramón y Cajal, IMSALUD, Madrid, Spain, CIBER en Epidemiología y Salud Pública (CIBERESP), Madrid, Spain, Unidad de Resistencia a Antibióticos y Virulencia Bacteriana asociada al Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain
⨯
Rafael Cantón,

Affiliations Hospital Universitario Ramón y Cajal, IMSALUD, Madrid, Spain, CIBER en Epidemiología y Salud Pública (CIBERESP), Madrid, Spain, Unidad de Resistencia a Antibióticos y Virulencia Bacteriana asociada al Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain
⨯
Teresa M. Coque,

Affiliations Hospital Universitario Ramón y Cajal, IMSALUD, Madrid, Spain, CIBER en Epidemiología y Salud Pública (CIBERESP), Madrid, Spain, Unidad de Resistencia a Antibióticos y Virulencia Bacteriana asociada al Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain
⨯
Andrés Moya,

Affiliations CIBER en Epidemiología y Salud Pública (CIBERESP), Madrid, Spain, Unidad Mixta Genómica y Salud CSISP/UV-Instituto Cavanilles, Valencia, Spain
⨯
Fernando González-Candelas ,

* E-mail: fernando.gonzalez@uv.es (FGC) (FG); jgalanm.hrc@salud.madrid.org (JCG) (JG)

Affiliations CIBER en Epidemiología y Salud Pública (CIBERESP), Madrid, Spain, Unidad Mixta Genómica y Salud CSISP/UV-Instituto Cavanilles, Valencia, Spain
⨯
Juan-Carlos Galán

* E-mail: fernando.gonzalez@uv.es (FGC) (FG); jgalanm.hrc@salud.madrid.org (JCG) (JG)

Affiliations Hospital Universitario Ramón y Cajal, IMSALUD, Madrid, Spain, CIBER en Epidemiología y Salud Pública (CIBERESP), Madrid, Spain, Unidad de Resistencia a Antibióticos y Virulencia Bacteriana asociada al Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain
⨯

Evolutionary Trajectories of Beta-Lactamase CTX-M-1 Cluster Enzymes: Predicting Antibiotic Resistance

Ângela Novais,
Iñaki Comas,
Fernando Baquero,
Rafael Cantón,
Teresa M. Coque,
Andrés Moya,
Fernando González-Candelas,
Juan-Carlos Galán

Published: January 22, 2010
https://doi.org/10.1371/journal.ppat.1000735

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