T Cell Detection of a B-Cell Tropic Virus Infection: Newly-Synthesised versus Mature Viral Proteins as Antigen Sources for CD4 and CD8 Epitope Display

Open Access

Peer-reviewed

Research Article

Laura K. Mackay,

Affiliation School of Cancer Sciences and MRC Centre for Immune Regulation, College of Medicine, University of Birmingham, Birmingham, United Kingdom
⨯
Heather M. Long,

Affiliation School of Cancer Sciences and MRC Centre for Immune Regulation, College of Medicine, University of Birmingham, Birmingham, United Kingdom
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Jill M. Brooks,

Affiliation School of Cancer Sciences and MRC Centre for Immune Regulation, College of Medicine, University of Birmingham, Birmingham, United Kingdom
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Graham S. Taylor,

Affiliation School of Cancer Sciences and MRC Centre for Immune Regulation, College of Medicine, University of Birmingham, Birmingham, United Kingdom
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Carol S. Leung,

Affiliation School of Cancer Sciences and MRC Centre for Immune Regulation, College of Medicine, University of Birmingham, Birmingham, United Kingdom
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Adrienne Chen,

Affiliation Department of Medicine, Brigham & Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
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Fred Wang,

Affiliation Department of Medicine, Brigham & Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
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Alan B. Rickinson

* E-mail: A.B.Rickinson@bham.ac.uk

Affiliation School of Cancer Sciences and MRC Centre for Immune Regulation, College of Medicine, University of Birmingham, Birmingham, United Kingdom
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T cells
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Cytotoxic T cells
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Major histocompatibility complex
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Antigen presentation
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Antigen processing and recognition
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Immunoblotting
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Protein expression
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Transfection
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