Degradation of Host Sphingomyelin Is Essential for Leishmania Virulence

Ou Zhang; Mattie C. Wilson; Wei Xu; Fong-Fu Hsu; John Turk; F. Matthew Kuhlmann; Yingwei Wang; Lynn Soong; Phillip Key; Stephen M. Beverley; Kai Zhang

doi:10.1371/journal.ppat.1000692

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Open Access

Peer-reviewed

Research Article

Degradation of Host Sphingomyelin Is Essential for Leishmania Virulence

Ou Zhang,

Affiliation Department of Biological Sciences, Texas Tech University, Lubbock, Texas, United States of America
⨯
Mattie C. Wilson,

Affiliation Department of Biological Sciences, Texas Tech University, Lubbock, Texas, United States of America
⨯
Wei Xu,

Affiliation Department of Biological Sciences, Texas Tech University, Lubbock, Texas, United States of America
⨯
Fong-Fu Hsu,

Affiliation Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri, United States of America
⨯
John Turk,

Affiliation Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri, United States of America
⨯
F. Matthew Kuhlmann,

Affiliation Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri, United States of America
⨯
Yingwei Wang,

Affiliation Department of Microbiology and Immunology, Department of Pathology, The University of Texas Medical Branch, Galveston, Texas, United States of America
⨯
Lynn Soong,

Affiliation Department of Microbiology and Immunology, Department of Pathology, The University of Texas Medical Branch, Galveston, Texas, United States of America
⨯
Phillip Key,

Affiliation Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, United States of America
⨯
Stephen M. Beverley,

Affiliation Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, United States of America
⨯
Kai Zhang

* E-mail: kai.zhang@ttu.edu

Affiliation Department of Biological Sciences, Texas Tech University, Lubbock, Texas, United States of America
⨯

Degradation of Host Sphingomyelin Is Essential for Leishmania Virulence

Ou Zhang,
Mattie C. Wilson,
Wei Xu,
Fong-Fu Hsu,
John Turk,
F. Matthew Kuhlmann,
Yingwei Wang,
Lynn Soong,
Phillip Key,
Stephen M. Beverley

Published: December 11, 2009
https://doi.org/10.1371/journal.ppat.1000692

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23 Dec 2009
14:11 GMT
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Publisher's Note: Correction to Figure 3 Posted by PLOS_Pathogens on 23 Dec 2009 at 14:11 GMT

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