Streptococcus pneumoniae Serotype 1 Capsular Polysaccharide Induces CD8⁺CD28⁻ Regulatory T Lymphocytes by TCR Crosslinking

• Janina Mertens ,

  Contributed equally to this work with: Janina Mertens, Mario Fabri

  Affiliation Institute for Medical Microbiology, Immunology and Hygiene, University of Cologne Medical Center, Köln, Germany

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• Mario Fabri ,

  Contributed equally to this work with: Janina Mertens, Mario Fabri

  Affiliation Institute for Medical Microbiology, Immunology and Hygiene, University of Cologne Medical Center, Köln, Germany

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• Alessandra Zingarelli,

  Affiliation Institute for Medical Microbiology, Immunology and Hygiene, University of Cologne Medical Center, Köln, Germany

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• Torsten Kubacki,

  Affiliation Institute for Medical Microbiology, Immunology and Hygiene, University of Cologne Medical Center, Köln, Germany

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• Sonja Meemboor,

  Affiliation Institute for Medical Microbiology, Immunology and Hygiene, University of Cologne Medical Center, Köln, Germany

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• Laura Groneck,

  Affiliation Institute for Medical Microbiology, Immunology and Hygiene, University of Cologne Medical Center, Köln, Germany

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• Jens Seeger,

  Affiliation Institute for Medical Microbiology, Immunology and Hygiene, University of Cologne Medical Center, Köln, Germany

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• Martina Bessler,

  Affiliation Institute for Medical Microbiology, Immunology and Hygiene, University of Cologne Medical Center, Köln, Germany

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• Helena Hafke,

  Affiliation Institute for Medical Microbiology, Immunology and Hygiene, University of Cologne Medical Center, Köln, Germany

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• Margarete Odenthal,

  Affiliation Department of Pathology, University of Cologne Medical Center, Köln, Germany

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• Joan G. Bieler,

  Affiliation Department of Pathology, Division of Immunopathology, Johns Hopkins School of Medicine, Baltimore, Maryland, United States of America

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• Christoph Kalka,

  Affiliation Swiss Cardiovascular Center, Division of Vascular Medicine, Inselspital, Bern University Hospital, and University of Bern, Freiburgstrasse, Bern, Switzerland

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• Jonathan P. Schneck,

  Affiliation Department of Pathology, Division of Immunopathology, Johns Hopkins School of Medicine, Baltimore, Maryland, United States of America

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• Hamid Kashkar,

  Affiliation Institute for Medical Microbiology, Immunology and Hygiene, University of Cologne Medical Center, Köln, Germany

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• Wiltrud M. Kalka-Moll

  * E-mail: wkalkamoll@labor-stein.de

  Current address: MVZ Dr. Stein + Kollegen, Mönchengladbach, Germany

  Affiliation Institute for Medical Microbiology, Immunology and Hygiene, University of Cologne Medical Center, Köln, Germany

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