CpG Methylation Controls Reactivation of HIV from Latency

Jana Blazkova; Katerina Trejbalova; Françoise Gondois-Rey; Philippe Halfon; Patrick Philibert; Allan Guiguen; Eric Verdin; Daniel Olive; Carine Van Lint; Jiri Hejnar; Ivan Hirsch

doi:10.1371/journal.ppat.1000554

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Peer-reviewed

Research Article

CpG Methylation Controls Reactivation of HIV from Latency

Jana Blazkova,

Affiliations Institut National de la Santé et de la Recherche Médicale (INSERM), UMR891, Centre de Recherche en Cancérologie de Marseille; and Institut Paoli-Calmettes, Marseille, France, Université Méditerranée, Marseille, France, Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, Prague, Czech Republic, Laboratory of Molecular Virology, Institute for Molecular Biology and Medicine (IBMM), University of Brussels (ULB), Gosselies, Belgium
⨯
Katerina Trejbalova,

Affiliations Institut National de la Santé et de la Recherche Médicale (INSERM), UMR891, Centre de Recherche en Cancérologie de Marseille; and Institut Paoli-Calmettes, Marseille, France, Université Méditerranée, Marseille, France, Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, Prague, Czech Republic
⨯
Françoise Gondois-Rey,

Affiliations Institut National de la Santé et de la Recherche Médicale (INSERM), UMR891, Centre de Recherche en Cancérologie de Marseille; and Institut Paoli-Calmettes, Marseille, France, Université Méditerranée, Marseille, France
⨯
Philippe Halfon,

Affiliation Department of Virology, Alphabio Laboratory, Marseilles, France
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Patrick Philibert,

Affiliation Department of Infectious Diseases, Hôpital Ambroise Paré, Marseilles, France
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Allan Guiguen,

Affiliation Laboratory of Molecular Virology, Institute for Molecular Biology and Medicine (IBMM), University of Brussels (ULB), Gosselies, Belgium
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Eric Verdin,

Affiliation Gladstone Institute of Virology and Immunology, San Francisco, California, United States of America
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Daniel Olive,

Affiliations Institut National de la Santé et de la Recherche Médicale (INSERM), UMR891, Centre de Recherche en Cancérologie de Marseille; and Institut Paoli-Calmettes, Marseille, France, Université Méditerranée, Marseille, France
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Carine Van Lint,

Affiliation Laboratory of Molecular Virology, Institute for Molecular Biology and Medicine (IBMM), University of Brussels (ULB), Gosselies, Belgium
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Jiri Hejnar,

Affiliation Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, Prague, Czech Republic
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Ivan Hirsch

* E-mail: ivan.hirsch@inserm.fr

Affiliations Institut National de la Santé et de la Recherche Médicale (INSERM), UMR891, Centre de Recherche en Cancérologie de Marseille; and Institut Paoli-Calmettes, Marseille, France, Université Méditerranée, Marseille, France
⨯

CpG Methylation Controls Reactivation of HIV from Latency

Jana Blazkova,
Katerina Trejbalova,
Françoise Gondois-Rey,
Philippe Halfon,
Patrick Philibert,
Allan Guiguen,
Eric Verdin,
Daniel Olive,
Carine Van Lint,
Jiri Hejnar

Published: August 21, 2009
https://doi.org/10.1371/journal.ppat.1000554

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DNA methylation
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HIV-1
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T cells
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Cloning
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Chromatin
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Immunoprecipitation
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Viral replication
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Histones
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