Mycobacterium tuberculosis Universal Stress Protein Rv2623 Regulates Bacillary Growth by ATP-Binding: Requirement for Establishing Chronic Persistent Infection

Joshua E. Drumm; Kaixia Mi; Patrick Bilder; Meihao Sun; Jihyeon Lim; Helle Bielefeldt-Ohmann; Randall Basaraba; Melvin So; Guofeng Zhu; JoAnn M. Tufariello; Angelo A. Izzo; Ian M. Orme; Steve C. Almo; Thomas S. Leyh; John Chan

doi:10.1371/journal.ppat.1000460

Loading metrics

Open Access

Peer-reviewed

Research Article

Mycobacterium tuberculosis Universal Stress Protein Rv2623 Regulates Bacillary Growth by ATP-Binding: Requirement for Establishing Chronic Persistent Infection

Joshua E. Drumm ,

Contributed equally to this work with: Joshua E. Drumm, Kaixia Mi

Affiliation Department of Medicine, Albert Einstein College of Medicine, Bronx, New York, United States of America
⨯
Kaixia Mi ,

Contributed equally to this work with: Joshua E. Drumm, Kaixia Mi

Affiliation Department of Microbiology & Immunology, Albert Einstein College of Medicine, Bronx, New York, United States of America
⨯
Patrick Bilder,

Affiliations Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, United States of America, Department of Physiology & Biophysics, Albert Einstein College of Medicine, Bronx, New York, United States of America
⨯
Meihao Sun,

Affiliation Department of Microbiology & Immunology, Albert Einstein College of Medicine, Bronx, New York, United States of America
⨯
Jihyeon Lim,

Affiliation Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, United States of America
⨯
Helle Bielefeldt-Ohmann,

Affiliation Mycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, United States of America
⨯
Randall Basaraba,

Affiliation Mycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, United States of America
⨯
Melvin So,

Affiliation Department of Microbiology & Immunology, Albert Einstein College of Medicine, Bronx, New York, United States of America
⨯
Guofeng Zhu,

Affiliation Department of Medicine, Albert Einstein College of Medicine, Bronx, New York, United States of America
⨯
JoAnn M. Tufariello,

Affiliation Department of Medicine, Albert Einstein College of Medicine, Bronx, New York, United States of America
⨯
Angelo A. Izzo,

Affiliation Mycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, United States of America
⨯
Ian M. Orme,

Affiliation Mycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, United States of America
⨯
Steve C. Almo,

Affiliations Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, United States of America, Department of Physiology & Biophysics, Albert Einstein College of Medicine, Bronx, New York, United States of America
⨯
Thomas S. Leyh,

Affiliation Department of Microbiology & Immunology, Albert Einstein College of Medicine, Bronx, New York, United States of America
⨯
John Chan

* E-mail: jchan@aecom.yu.edu

Affiliations Department of Medicine, Albert Einstein College of Medicine, Bronx, New York, United States of America, Department of Microbiology & Immunology, Albert Einstein College of Medicine, Bronx, New York, United States of America
⨯

Mycobacterium tuberculosis Universal Stress Protein Rv2623 Regulates Bacillary Growth by ATP-Binding: Requirement for Establishing Chronic Persistent Infection

Joshua E. Drumm,
Kaixia Mi,
Patrick Bilder,
Meihao Sun,
Jihyeon Lim,
Helle Bielefeldt-Ohmann,
Randall Basaraba,
Melvin So,
Guofeng Zhu,
JoAnn M. Tufariello

Published: May 29, 2009
https://doi.org/10.1371/journal.ppat.1000460

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Mycobacterium tuberculosis
Is the Subject Area "Mycobacterium tuberculosis" applicable to this article?

Thanks for your feedback.
Nucleotides
Is the Subject Area "Nucleotides" applicable to this article?

Thanks for your feedback.
Guinea pigs
Is the Subject Area "Guinea pigs" applicable to this article?

Thanks for your feedback.
Crystal structure
Is the Subject Area "Crystal structure" applicable to this article?

Thanks for your feedback.
Hyperexpression techniques
Is the Subject Area "Hyperexpression techniques" applicable to this article?

Thanks for your feedback.
Regulons
Is the Subject Area "Regulons" applicable to this article?

Thanks for your feedback.
Dimers
Is the Subject Area "Dimers" applicable to this article?

Thanks for your feedback.
Tuberculosis
Is the Subject Area "Tuberculosis" applicable to this article?

Thanks for your feedback.