Parasite-Dependent Expansion of TNF Receptor II–Positive Regulatory T Cells with Enhanced Suppressive Activity in Adults with Severe Malaria

Gabriela Minigo; Tonia Woodberry; Kim A. Piera; Ervi Salwati; Emiliana Tjitra; Enny Kenangalem; Ric N. Price; Christian R. Engwerda; Nicholas M. Anstey; Magdalena Plebanski

doi:10.1371/journal.ppat.1000402

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Open Access

Peer-reviewed

Research Article

Parasite-Dependent Expansion of TNF Receptor II–Positive Regulatory T Cells with Enhanced Suppressive Activity in Adults with Severe Malaria

Gabriela Minigo ,

Contributed equally to this work with: Gabriela Minigo, Tonia Woodberry

Affiliations Department of Immunology, Monash University, Alfred Medical Research and Education Precinct, Melbourne, Australia, International Health Division, Menzies School of Health Research (MSHR) and Charles Darwin University, Darwin, Australia
⨯
Tonia Woodberry ,

Contributed equally to this work with: Gabriela Minigo, Tonia Woodberry

Affiliation International Health Division, Menzies School of Health Research (MSHR) and Charles Darwin University, Darwin, Australia
⨯
Kim A. Piera,

Affiliation International Health Division, Menzies School of Health Research (MSHR) and Charles Darwin University, Darwin, Australia
⨯
Ervi Salwati,

Affiliation National Institute of Health Research and Development (NIHRD), Ministry of Health, Jakarta, Indonesia
⨯
Emiliana Tjitra,

Affiliation National Institute of Health Research and Development (NIHRD), Ministry of Health, Jakarta, Indonesia
⨯
Enny Kenangalem,

Affiliation NIHRD-MSHR Collaborative Research Program and District Health Authority, Timika, Papua, Indonesia
⨯
Ric N. Price,

Affiliations International Health Division, Menzies School of Health Research (MSHR) and Charles Darwin University, Darwin, Australia, Centre for Vaccinology and Tropical Medicine, Nuffield Department of Clinical Medicine, Churchill Hospital, Oxford, United Kingdom
⨯
Christian R. Engwerda,

Affiliation Queensland Institute of Medical Research, Brisbane, Australia
⨯
Nicholas M. Anstey ,

¶These authors contributed equally to this work.

Affiliation International Health Division, Menzies School of Health Research (MSHR) and Charles Darwin University, Darwin, Australia
⨯
Magdalena Plebanski

* E-mail: Magdalena.Plebanski@med.monash.edu.au

¶These authors contributed equally to this work.

Affiliation Department of Immunology, Monash University, Alfred Medical Research and Education Precinct, Melbourne, Australia
⨯

Parasite-Dependent Expansion of TNF Receptor II–Positive Regulatory T Cells with Enhanced Suppressive Activity in Adults with Severe Malaria

Gabriela Minigo,
Tonia Woodberry,
Kim A. Piera,
Ervi Salwati,
Emiliana Tjitra,
Enny Kenangalem,
Ric N. Price,
Christian R. Engwerda,
Nicholas M. Anstey,
Magdalena Plebanski

Published: April 24, 2009
https://doi.org/10.1371/journal.ppat.1000402

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Regulatory T cells
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Malaria
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