High Throughput Functional Assays of the Variant Antigen PfEMP1 Reveal a Single Domain in the 3D7 Plasmodium falciparum Genome that Binds ICAM1 with High Affinity and Is Targeted by Naturally Acquired Neutralizing Antibodies

• Andrew V. Oleinikov ,

  * E-mail: andrew.oleinikov@sbri.org

  Affiliation Seattle Biomedical Research Institute, Seattle, Washington, United States of America

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• Emily Amos,

  Affiliation Seattle Biomedical Research Institute, Seattle, Washington, United States of America

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• Isaac Tyler Frye,

  Affiliation Seattle Biomedical Research Institute, Seattle, Washington, United States of America

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• Eddie Rossnagle,

  Affiliation Seattle Biomedical Research Institute, Seattle, Washington, United States of America

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• Theonest K. Mutabingwa,

  Affiliations Seattle Biomedical Research Institute, Seattle, Washington, United States of America, National Institute for Medical Research, Dar es Salaam, Tanzania

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• Michal Fried,

  Affiliations Seattle Biomedical Research Institute, Seattle, Washington, United States of America, Department of Global Health, University of Washington, Seattle, Washington, United States of America

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• Patrick E. Duffy

  Affiliations Seattle Biomedical Research Institute, Seattle, Washington, United States of America, Department of Global Health, University of Washington, Seattle, Washington, United States of America

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