Host-Species Transferrin Receptor 1 Orthologs Are Cellular Receptors for Nonpathogenic New World Clade B Arenaviruses

Jonathan Abraham; Jo Ann Kwong; César G. Albariño; Jiajie G. Lu; Sheli R. Radoshitzky; Jorge Salazar-Bravo; Michael Farzan; Christina F. Spiropoulou; Hyeryun Choe

doi:10.1371/journal.ppat.1000358

Loading metrics

Open Access

Peer-reviewed

Research Article

Host-Species Transferrin Receptor 1 Orthologs Are Cellular Receptors for Nonpathogenic New World Clade B Arenaviruses

Jonathan Abraham ,

Contributed equally to this work with: Jonathan Abraham, Jo Ann Kwong

Affiliations Department of Medicine, Children's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America, Laboratory of Molecular Medicine, Children's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America, Howard Hughes Medical Institute, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Jo Ann Kwong ,

Contributed equally to this work with: Jonathan Abraham, Jo Ann Kwong

Affiliation Department of Medicine, Children's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
César G. Albariño,

Affiliation Special Pathogens Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
⨯
Jiajie G. Lu,

Affiliation Department of Medicine, Children's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Sheli R. Radoshitzky,

Affiliation Department of Microbiology and Molecular Genetics, Harvard Medical School, New England Primate Center, Southborough, Massachusetts, United States of America
⨯
Jorge Salazar-Bravo,

Affiliation Department of Biological Sciences, Texas Tech University, Lubbock, Texas, United States of America
⨯
Michael Farzan,

Affiliation Department of Microbiology and Molecular Genetics, Harvard Medical School, New England Primate Center, Southborough, Massachusetts, United States of America
⨯
Christina F. Spiropoulou ,

* E-mail: ccs8@cdc.gov (CFS); hyeryun.choe@childrens.harvard.edu (HC)

Affiliation Special Pathogens Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
⨯
Hyeryun Choe

* E-mail: ccs8@cdc.gov (CFS); hyeryun.choe@childrens.harvard.edu (HC)

Affiliation Department of Medicine, Children's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
⨯

Host-Species Transferrin Receptor 1 Orthologs Are Cellular Receptors for Nonpathogenic New World Clade B Arenaviruses

Jonathan Abraham,
Jo Ann Kwong,
César G. Albariño,
Jiajie G. Lu,
Sheli R. Radoshitzky,
Jorge Salazar-Bravo,
Michael Farzan,
Christina F. Spiropoulou,
Hyeryun Choe

Published: April 3, 2009
https://doi.org/10.1371/journal.ppat.1000358

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Arenaviruses
Is the Subject Area "Arenaviruses" applicable to this article?

Thanks for your feedback.
Hemorrhagic fever viruses
Is the Subject Area "Hemorrhagic fever viruses" applicable to this article?

Thanks for your feedback.
Chapare virus
Is the Subject Area "Chapare virus" applicable to this article?

Thanks for your feedback.
Viral pathogens
Is the Subject Area "Viral pathogens" applicable to this article?

Thanks for your feedback.
Flow cytometry
Is the Subject Area "Flow cytometry" applicable to this article?

Thanks for your feedback.
Transfection
Is the Subject Area "Transfection" applicable to this article?

Thanks for your feedback.
Guanarito virus
Is the Subject Area "Guanarito virus" applicable to this article?

Thanks for your feedback.
Machupo virus
Is the Subject Area "Machupo virus" applicable to this article?

Thanks for your feedback.