Studies of a Ring-Cleaving Dioxygenase Illuminate the Role of Cholesterol Metabolism in the Pathogenesis of Mycobacterium tuberculosis

• Katherine C. Yam ,

  Contributed equally to this work with: Katherine C. Yam, Igor D'Angelo, Rainer Kalscheuer

  Affiliation Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada

  ⨯
• Igor D'Angelo ,

  Contributed equally to this work with: Katherine C. Yam, Igor D'Angelo, Rainer Kalscheuer

  Affiliation Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada

  ⨯
• Rainer Kalscheuer ,

  Contributed equally to this work with: Katherine C. Yam, Igor D'Angelo, Rainer Kalscheuer

  Affiliation Howard Hughes Medical Institute, Albert Einstein College of Medicine, Bronx, New York, United States of America

  ⨯
• Haizhong Zhu,

  Current address: Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada

  Affiliation Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada

  ⨯
• Jian-Xin Wang,

  Affiliation Department of Chemistry, Queen's University, Kingston, Ontario, Canada

  ⨯
• Victor Snieckus,

  Affiliation Department of Chemistry, Queen's University, Kingston, Ontario, Canada

  ⨯
• Lan H. Ly,

  Affiliation Department of Microbial and Molecular Pathogenesis, Texas A&M University Health Science Center, College Station, Texas, United States of America

  ⨯
• Paul J. Converse,

  Affiliation Center for Tuberculosis Research, Department of Medicine, Johns Hopkins University, Baltimore, Maryland, United States of America

  ⨯
• William R. Jacobs Jr.,

  Affiliation Howard Hughes Medical Institute, Albert Einstein College of Medicine, Bronx, New York, United States of America

  ⨯
• Natalie Strynadka,

  Affiliation Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada

  ⨯
• Lindsay D. Eltis

  * E-mail: leltis@interchange.ubc.ca

  Affiliations Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada, Department of Microbiology and Immunology, University of British Columbia, Vancouver, British Columbia, Canada

  ⨯