Receptor Complementation and Mutagenesis Reveal SR-BI as an Essential HCV Entry Factor and Functionally Imply Its Intra- and Extra-Cellular Domains

Marlène Dreux; Viet Loan Dao Thi; Judith Fresquet; Maryse Guérin; Zélie Julia; Géraldine Verney; David Durantel; Fabien Zoulim; Dimitri Lavillette; François-Loïc Cosset; Birke Bartosch

doi:10.1371/journal.ppat.1000310

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Peer-reviewed

Research Article

Receptor Complementation and Mutagenesis Reveal SR-BI as an Essential HCV Entry Factor and Functionally Imply Its Intra- and Extra-Cellular Domains

Marlène Dreux,

Affiliation Université de Lyon, UCB-Lyon1, IFR128; INSERM, U758; Ecole Normale Supérieure de Lyon, Lyon, France
⨯
Viet Loan Dao Thi ,

Contributed equally to this work with: Viet Loan Dao Thi, Judith Fresquet

Affiliation Université de Lyon, UCB-Lyon1, IFR128; INSERM, U758; Ecole Normale Supérieure de Lyon, Lyon, France
⨯
Judith Fresquet ,

Contributed equally to this work with: Viet Loan Dao Thi, Judith Fresquet

Affiliation Université de Lyon, UCB-Lyon1, IFR128; INSERM, U758; Ecole Normale Supérieure de Lyon, Lyon, France
⨯
Maryse Guérin,

Affiliation INSERM, U551, Paris, France
⨯
Zélie Julia,

Affiliation INSERM, U551, Paris, France
⨯
Géraldine Verney,

Affiliation Université de Lyon, UCB-Lyon1, IFR128; INSERM, U758; Ecole Normale Supérieure de Lyon, Lyon, France
⨯
David Durantel,

Affiliation Université de Lyon, UCB-Lyon1, IFR62; INSERM, U871; Hospices civils de Lyon (HCL), Lyon, France
⨯
Fabien Zoulim,

Affiliation Université de Lyon, UCB-Lyon1, IFR62; INSERM, U871; Hospices civils de Lyon (HCL), Lyon, France
⨯
Dimitri Lavillette,

Affiliation Université de Lyon, UCB-Lyon1, IFR128; INSERM, U758; Ecole Normale Supérieure de Lyon, Lyon, France
⨯
François-Loïc Cosset ,

* E-mail: flcosset@ens-lyon.fr

¶These authors contributed equally to this work.

Affiliation Université de Lyon, UCB-Lyon1, IFR128; INSERM, U758; Ecole Normale Supérieure de Lyon, Lyon, France
⨯
Birke Bartosch

¶These authors contributed equally to this work.

Affiliation Université de Lyon, UCB-Lyon1, IFR128; INSERM, U758; Ecole Normale Supérieure de Lyon, Lyon, France
⨯

Receptor Complementation and Mutagenesis Reveal SR-BI as an Essential HCV Entry Factor and Functionally Imply Its Intra- and Extra-Cellular Domains

Marlène Dreux,
Viet Loan Dao Thi,
Judith Fresquet,
Maryse Guérin,
Zélie Julia,
Géraldine Verney,
David Durantel,
Fabien Zoulim,
Dimitri Lavillette,
François-Loïc Cosset

Published: February 20, 2009
https://doi.org/10.1371/journal.ppat.1000310

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