A Sterol-Regulatory Element Binding Protein Is Required for Cell Polarity, Hypoxia Adaptation, Azole Drug Resistance, and Virulence in Aspergillus fumigatus

Sven D. Willger; Srisombat Puttikamonkul; Kwang-Hyung Kim; James B. Burritt; Nora Grahl; Laurel J. Metzler; Robert Barbuch; Martin Bard; Christopher B. Lawrence; Robert A. Cramer Jr.

doi:10.1371/journal.ppat.1000200

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Peer-reviewed

Research Article

A Sterol-Regulatory Element Binding Protein Is Required for Cell Polarity, Hypoxia Adaptation, Azole Drug Resistance, and Virulence in Aspergillus fumigatus

Sven D. Willger,

Affiliation Department of Veterinary Molecular Biology, Montana State University, Bozeman, Montana, United States of America
⨯
Srisombat Puttikamonkul,

Affiliation Department of Veterinary Molecular Biology, Montana State University, Bozeman, Montana, United States of America
⨯
Kwang-Hyung Kim,

Affiliation Virginia Bioinformatics Institute, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, United States of America
⨯
James B. Burritt,

Affiliation Department of Microbiology, Montana State University, Bozeman, Montana, United States of America
⨯
Nora Grahl,

Affiliation Department of Veterinary Molecular Biology, Montana State University, Bozeman, Montana, United States of America
⨯
Laurel J. Metzler,

Affiliation Department of Biology, Indiana University-Purdue University, Indianapolis, Indiana, United States of America
⨯
Robert Barbuch,

Affiliation Department of Biology, Indiana University-Purdue University, Indianapolis, Indiana, United States of America
⨯
Martin Bard,

Affiliation Department of Biology, Indiana University-Purdue University, Indianapolis, Indiana, United States of America
⨯
Christopher B. Lawrence,

Affiliation Virginia Bioinformatics Institute, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, United States of America
⨯
Robert A. Cramer Jr.

* E-mail: rcramer@montana.edu

Affiliation Department of Veterinary Molecular Biology, Montana State University, Bozeman, Montana, United States of America
⨯

A Sterol-Regulatory Element Binding Protein Is Required for Cell Polarity, Hypoxia Adaptation, Azole Drug Resistance, and Virulence in Aspergillus fumigatus

Sven D. Willger,
Srisombat Puttikamonkul,
Kwang-Hyung Kim,
James B. Burritt,
Nora Grahl,
Laurel J. Metzler,
Robert Barbuch,
Martin Bard,
Christopher B. Lawrence,
Robert A. Cramer Jr.

Published: November 7, 2008
https://doi.org/10.1371/journal.ppat.1000200

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