CD4-Specific Designed Ankyrin Repeat Proteins Are Novel Potent HIV Entry Inhibitors with Unique Characteristics

Andreas Schweizer; Peter Rusert; Livia Berlinger; Claudia R. Ruprecht; Axel Mann; Stéphanie Corthésy; Stuart G. Turville; Meropi Aravantinou; Marek Fischer; Melissa Robbiani; Patrick Amstutz; Alexandra Trkola

doi:10.1371/journal.ppat.1000109

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Open Access

Peer-reviewed

Research Article

CD4-Specific Designed Ankyrin Repeat Proteins Are Novel Potent HIV Entry Inhibitors with Unique Characteristics

Andreas Schweizer,

Affiliation Division of Infectious Diseases, University Hospital Zurich, Zurich, Switzerland
⨯
Peter Rusert,

Affiliation Division of Infectious Diseases, University Hospital Zurich, Zurich, Switzerland
⨯
Livia Berlinger,

Affiliation Division of Infectious Diseases, University Hospital Zurich, Zurich, Switzerland
⨯
Claudia R. Ruprecht,

Affiliation Division of Infectious Diseases, University Hospital Zurich, Zurich, Switzerland
⨯
Axel Mann,

Affiliation Division of Infectious Diseases, University Hospital Zurich, Zurich, Switzerland
⨯
Stéphanie Corthésy,

Affiliation Division of Infectious Diseases, University Hospital Zurich, Zurich, Switzerland
⨯
Stuart G. Turville,

Current address: Center for Virus Research, Westmead Millennium Institute, Westmead Hospital and University of Sydney, Sydney, New South Wales, Australia

Affiliation Center for Biomedical Research, Population Council, New York, New York, United States of America
⨯
Meropi Aravantinou,

Affiliation Center for Biomedical Research, Population Council, New York, New York, United States of America
⨯
Marek Fischer,

Affiliation Division of Infectious Diseases, University Hospital Zurich, Zurich, Switzerland
⨯
Melissa Robbiani,

Affiliation Center for Biomedical Research, Population Council, New York, New York, United States of America
⨯
Patrick Amstutz,

Affiliation Molecular Partners AG, Zurich-Schlieren, Switzerland
⨯
Alexandra Trkola

* E-mail: alexandra.trkola@usz.ch

Affiliation Division of Infectious Diseases, University Hospital Zurich, Zurich, Switzerland
⨯

CD4-Specific Designed Ankyrin Repeat Proteins Are Novel Potent HIV Entry Inhibitors with Unique Characteristics

Andreas Schweizer,
Peter Rusert,
Livia Berlinger,
Claudia R. Ruprecht,
Axel Mann,
Stéphanie Corthésy,
Stuart G. Turville,
Meropi Aravantinou,
Marek Fischer,
Melissa Robbiani

Published: July 25, 2008
https://doi.org/10.1371/journal.ppat.1000109

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