HIV-1 Vpr-Mediated G2 Arrest Involves the DDB1-CUL4AVPRBP E3 Ubiquitin Ligase

Open Access

Peer-reviewed

Research Article

HIV-1 Vpr-Mediated G2 Arrest Involves the DDB1-CUL4A^VPRBP E3 Ubiquitin Ligase

Jean-Philippe Belzile ,

Contributed equally to this work with: Jean-Philippe Belzile, Ghislaine Duisit

Affiliation Laboratory of Human Retrovirology, Institut de Recherches Cliniques de Montréal, Montreal, Quebec, Canada
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Ghislaine Duisit ,

Contributed equally to this work with: Jean-Philippe Belzile, Ghislaine Duisit

¤ Current address: Centre de Thérapie Génique, Faculté de Médecine, Marseille, France

Affiliation Department of Microbiology and Immunology, Université de Montréal, Montreal, Quebec, Canada
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Nicole Rougeau,

Affiliation Laboratory of Human Retrovirology, Institut de Recherches Cliniques de Montréal, Montreal, Quebec, Canada
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Johanne Mercier,

Affiliation Laboratory of Human Retrovirology, Institut de Recherches Cliniques de Montréal, Montreal, Quebec, Canada
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Andrés Finzi,

Affiliation Laboratory of Human Retrovirology, Institut de Recherches Cliniques de Montréal, Montreal, Quebec, Canada
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Éric A Cohen

*To whom correspondence should be addressed. E-mail: eric.cohen@ircm.qc.ca

Affiliations Laboratory of Human Retrovirology, Institut de Recherches Cliniques de Montréal, Montreal, Quebec, Canada , Department of Microbiology and Immunology, Université de Montréal, Montreal, Quebec, Canada
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Transfection
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Immunoprecipitation
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Small interfering RNA
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Cell cycle and cell division
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Plasmid construction
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DNA-binding proteins
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Ubiquitin ligases
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Protein interactions
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