LRP5 and LRP6 Are Not Required for Protective Antigen–Mediated Internalization or Lethality of Anthrax Lethal Toxin

John J Young; Jennifer L Bromberg-White; Cassandra Zylstra; Joseph T Church; Elissa Boguslawski; James H Resau; Bart O Williams; Nicholas S Duesbery

doi:10.1371/journal.ppat.0030027

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Peer-reviewed

Research Article

LRP5 and LRP6 Are Not Required for Protective Antigen–Mediated Internalization or Lethality of Anthrax Lethal Toxin

John J Young ,

Contributed equally to this work with: John J Young, Jennifer L Bromberg-White

Affiliation Laboratory of Cancer and Developmental Cell Biology, Van Andel Research Institute, Grand Rapids, Michigan, United States of America
⨯
Jennifer L Bromberg-White ,

Contributed equally to this work with: John J Young, Jennifer L Bromberg-White

Affiliation Laboratory of Cancer and Developmental Cell Biology, Van Andel Research Institute, Grand Rapids, Michigan, United States of America
⨯
Cassandra Zylstra,

Affiliation Laboratory of Cell Signaling and Carcinogenesis, Van Andel Research Institute, Grand Rapids, Michigan, United States of America
⨯
Joseph T Church,

Affiliation Laboratory of Cancer and Developmental Cell Biology, Van Andel Research Institute, Grand Rapids, Michigan, United States of America
⨯
Elissa Boguslawski,

Affiliation Laboratory of Cancer and Developmental Cell Biology, Van Andel Research Institute, Grand Rapids, Michigan, United States of America
⨯
James H Resau,

Affiliation Laboratory of Analytical, Cellular, and Molecular Microscopy, Van Andel Research Institute, Grand Rapids, Michigan, United States of America
⨯
Bart O Williams,

Affiliation Laboratory of Cell Signaling and Carcinogenesis, Van Andel Research Institute, Grand Rapids, Michigan, United States of America
⨯
Nicholas S Duesbery

*To whom correspondence should be addressed. E-mail: duesbery@vai.org

Affiliation Laboratory of Cancer and Developmental Cell Biology, Van Andel Research Institute, Grand Rapids, Michigan, United States of America
⨯

LRP5 and LRP6 Are Not Required for Protective Antigen–Mediated Internalization or Lethality of Anthrax Lethal Toxin

John J Young,
Jennifer L Bromberg-White,
Cassandra Zylstra,
Joseph T Church,
Elissa Boguslawski,
James H Resau,
Bart O Williams,
Nicholas S Duesbery

Published: March 2, 2007
https://doi.org/10.1371/journal.ppat.0030027

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