Inefficient Nef-Mediated Downmodulation of CD3 and MHC-I Correlates with Loss of CD4⁺ T Cells in Natural SIV Infection

• Michael Schindler,

  Current address: Heinrich-Pette-Institut, Hamburg, Germany

  Affiliation Institute of Virology, University of Ulm, Germany

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• Jan Schmökel,

  Affiliation Institute of Virology, University of Ulm, Germany

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• Anke Specht,

  Affiliation Institute of Virology, University of Ulm, Germany

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• Hui Li,

  Affiliation Departments of Medicine and Microbiology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America

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• Jan Münch,

  Affiliation Institute of Virology, University of Ulm, Germany

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• Mohammad Khalid,

  Affiliation Institute of Virology, University of Ulm, Germany

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• Donald L. Sodora,

  Affiliation University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

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• Beatrice H. Hahn,

  Affiliation Departments of Medicine and Microbiology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America

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• Guido Silvestri,

  Affiliations Yerkes Regional Primate Research Center, Emory University, Atlanta, Georgia, United States of America, Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

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• Frank Kirchhoff

  * E-mail: frank.kirchhoff@uniklinik-ulm.de

  Affiliation Institute of Virology, University of Ulm, Germany

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