Unique Structure and Stability of HmuY, a Novel Heme-Binding Protein of Porphyromonas gingivalis

Halina Wójtowicz; Tibisay Guevara; Cynthia Tallant; Mariusz Olczak; Aneta Sroka; Jan Potempa; Maria Solà; Teresa Olczak; F. Xavier Gomis-Rüth

doi:10.1371/journal.ppat.1000419

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Peer-reviewed

Research Article

Unique Structure and Stability of HmuY, a Novel Heme-Binding Protein of Porphyromonas gingivalis

Halina Wójtowicz ,

¶These authors contributed equally to this study and share first authorship.

Affiliation Laboratory of Biochemistry, Faculty of Biotechnology, University of Wroclaw, Wroclaw, Poland
⨯
Tibisay Guevara ,

¶These authors contributed equally to this study and share first authorship.

Affiliation Proteolysis Lab, Department of Structural Biology, Molecular Biology Institute of Barcelona, CSIC, Barcelona, Spain
⨯
Cynthia Tallant,

Affiliation Proteolysis Lab, Department of Structural Biology, Molecular Biology Institute of Barcelona, CSIC, Barcelona, Spain
⨯
Mariusz Olczak,

Affiliation Laboratory of Biochemistry, Faculty of Biotechnology, University of Wroclaw, Wroclaw, Poland
⨯
Aneta Sroka,

Affiliation Laboratory of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland
⨯
Jan Potempa,

Affiliations Laboratory of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland, Department of Periodontics, University of Louisville School of Dentistry, Louisville, Kentucky, United States of America
⨯
Maria Solà,

Affiliation Structural MitoLab, Department of Structural Biology, Molecular Biology Institute of Barcelona, CSIC, Barcelona, Spain
⨯
Teresa Olczak ,

* E-mail: Teresa.Olczak@biotech.uni.wroc.pl (TO); fxgr@ibmb.csic.es (FXG-R)

Affiliation Laboratory of Biochemistry, Faculty of Biotechnology, University of Wroclaw, Wroclaw, Poland
⨯
F. Xavier Gomis-Rüth

* E-mail: Teresa.Olczak@biotech.uni.wroc.pl (TO); fxgr@ibmb.csic.es (FXG-R)

Affiliation Proteolysis Lab, Department of Structural Biology, Molecular Biology Institute of Barcelona, CSIC, Barcelona, Spain
⨯

Unique Structure and Stability of HmuY, a Novel Heme-Binding Protein of Porphyromonas gingivalis

Halina Wójtowicz,
Tibisay Guevara,
Cynthia Tallant,
Mariusz Olczak,
Aneta Sroka,
Jan Potempa,
Maria Solà,
Teresa Olczak,
F. Xavier Gomis-Rüth

Published: May 8, 2009
https://doi.org/10.1371/journal.ppat.1000419

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Publisher's Note: Correction to Funding

Posted by PLOS_Pathogens on 11 May 2009 at 18:31 GMT

This
feature also facilitates heme transport to HmuR and into the bacterial cell. All
these data may help to develop new antibacterial agents at times in which
resistance toward antibiotics, both at intensive healthcare stations and in the
community, poses serious challenges to human health.
http://plospathogens.org/article/info:doi/10.1371/journal.ppat.1000419#article1.front1.article-meta1.abstract2.p1

There was an error in the first sentence of the Funding section. Grant BIO2009-XXXXX should read BIO200910334.

No competing interests declared.

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Heme
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Protein interactions
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Denaturation
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Fluorescence
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Fingers
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Proteases
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Proteolysis
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Unique Structure and Stability of HmuY, a Novel Heme-Binding Protein of Porphyromonas gingivalis

Unique Structure and Stability of HmuY, a Novel Heme-Binding Protein of Porphyromonas gingivalis

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Publisher's Note: Correction to Funding

Posted by PLOS_Pathogens on 11 May 2009 at 18:31 GMT