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closeuncertain origin.
Posted by pgagne on 25 Jun 2021 at 21:54 GMT
These results seems interesting. They match with other observations. But couldn't those results be interpreted as a probability of origin instead of a date of origin ? It seems by those data that China is the most probable source, but not the only possible one. You seems to estimate the apparition of covid-19 in China as November 17 while also allowing it to be possibly in Italy as soon as Nov 3 (2.5% chance). Is there any reason to exclude it ? The origin point seems very movable still.
On another note, doesn't the technique used rely heavily on the assumption that equal efforts were produced to detect covid-19 all over the world. Which seems erroneous to some extent. I remember that very little tests were made in America during January or February. Your results seems to show that it could have been done if it was tried. On the other side, you have a first detection in Wuhan but it was realistically one of very few labs that would have done a genetic sequencing of a coronavirus unprompted. Which most likely played a huge role in the fact that it was detected there first. It's not quite like observing a bear in your backyard.
All this to say that the 95% certainty claims seems a little presumptuous. By shuffling a bit the point of origin and factoring for the difficulty of detecting covid-19, specially in early stage, I'm sure we could have a good chance to push the origin date in september, maybe even august.
These dates seems good IF covid originated from Wuhan. But those results also show, it might not be the case.
RE: uncertain origin.
David_Roberts replied to pgagne on 26 Jun 2021 at 21:52 GMT
Many thanks, for your comment there is a lot to try and unpack here but happy to discuss further if you email me. However regarding the search effort, the method has been tested under a range of scenarios and found to be robust e.g.
Rivadeneira MM, Hunt G, Roy K. The use of sighting records to infer species extinctions: an evaluation of different methods. Ecology 2009;90: 1291–1300.
Clements CF, Worsfold NT, Warren PH, Collen B, Clark N, Blackburn TM, et al. Experimentally testing the accuracy of an extinction estimator: Solow’s optimal linear estimation model. J Anim Ecol. 2013;82: 345–54.
RE: RE: uncertain origin.
pgagne replied to David_Roberts on 01 Jul 2021 at 19:20 GMT
I appreciate the method used. And I see other comments here cover mostly what I said.
I'll just reiterate more concisely that there seems to be an assumption that the first case was precisely in Wuhan. You give a 95% chance time window for different countries. But that time window doesn't always give Wuhan as the first case.
I believe this method could be reiterated to give "better" results. By using this first result to estimate the chance or origin in other regions and then rerun the method for each possibility and then sum the maps for an overall estimation. If that make sens.