Trypanosoma brucei PUF9 Regulates mRNAs for Proteins Involved in Replicative Processes over the Cell Cycle

Stuart K. Archer; Van-Duc Luu; Rafael A. de Queiroz; Stefanie Brems; Christine Clayton

doi:10.1371/journal.ppat.1000565

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Trypanosoma brucei PUF9 Regulates mRNAs for Proteins Involved in Replicative Processes over the Cell Cycle

Stuart K. Archer ,

* E-mail: s.archer@zmbh.uni-heidelberg.de

Affiliation Zentrum für Molekulare Biologie Heidelberg, DKFZ-ZMBH Allianz, Heidelberg, Germany
⨯
Van-Duc Luu,

Affiliation Zentrum für Molekulare Biologie Heidelberg, DKFZ-ZMBH Allianz, Heidelberg, Germany
⨯
Rafael A. de Queiroz,

Affiliation Deutsches Krebsforschungszentrum, DKFZ-ZMBH Allianz, Heidelberg, Germany
⨯
Stefanie Brems,

Affiliation Deutsches Krebsforschungszentrum, DKFZ-ZMBH Allianz, Heidelberg, Germany
⨯
Christine Clayton

Affiliation Zentrum für Molekulare Biologie Heidelberg, DKFZ-ZMBH Allianz, Heidelberg, Germany
⨯

Trypanosoma brucei PUF9 Regulates mRNAs for Proteins Involved in Replicative Processes over the Cell Cycle

Stuart K. Archer,
Van-Duc Luu,
Rafael A. de Queiroz,
Stefanie Brems,
Christine Clayton

Published: August 28, 2009
https://doi.org/10.1371/journal.ppat.1000565

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Publisher's Note: Correction to Gene Name PNT2

Posted by PLOS_Pathogens on 10 Sep 2009 at 22:26 GMT

PNT2
http://plospathogens.org/article/info:doi/10.1371/journal.ppat.1000565#article1.front1.article-meta1.abstract1.p1

The protein encoded by the Trypanosoma brucei gene Tb11.01.6470 and referred to as Puf Nine Target 2 (PNT2) in this paper is actually TbCPC2. TbCPC2 was characterized in [1] as a component of the T. brucei chromosomal passenger complex, which is an important coordinator of chromosomal and cytoskeletal events in eukaryotic mitosis. Thus, TbCPC2 is post-transcriptionally regulated in coordination with the cell cycle by PUF9 in T. brucei.

The adoption of original name for the gene, TbCPC2, is encouraged for further studies.

1. Li Z, Lee JH, Chu F, Burlingame AL, Gunzl A, et al. (2008) Identification of a novel chromosomal passenger complex and its unique localization during cytokinesis in Trypanosoma brucei. PLoS ONE 3: e2354.

No competing interests declared.

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Kinetoplasts
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RNA interference
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Cell cycle and cell division
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Messenger RNA
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Trypanosoma brucei gambiense
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Trypanosoma brucei PUF9 Regulates mRNAs for Proteins Involved in Replicative Processes over the Cell Cycle

Trypanosoma brucei PUF9 Regulates mRNAs for Proteins Involved in Replicative Processes over the Cell Cycle

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Publisher's Note: Correction to Gene Name PNT2

Posted by PLOS_Pathogens on 10 Sep 2009 at 22:26 GMT