About the Authors

Lorena C. S. Chaves

Contributed equally to this work with: Lorena C. S. Chaves, Nichole Orr-Burks

Roles Formal analysis, Investigation, Methodology, Visualization, Writing – original draft

Affiliation Wallace H. Coulter Department of Biomedical Engineering, Emory University and Georgia Institute of Technology, Atlanta, Georgia, United States of America

Nichole Orr-Burks

Contributed equally to this work with: Lorena C. S. Chaves, Nichole Orr-Burks

Roles Formal analysis, Investigation, Methodology, Writing – original draft

Affiliation Department of Infectious Diseases, College of Veterinary Medicine University of Georgia, Athens, Georgia, United States of America

Daryll Vanover

Roles Formal analysis, Investigation, Methodology, Visualization

Affiliation Wallace H. Coulter Department of Biomedical Engineering, Emory University and Georgia Institute of Technology, Atlanta, Georgia, United States of America

Varun V. Mosur

Roles Investigation, Methodology

Affiliation Wallace H. Coulter Department of Biomedical Engineering, Emory University and Georgia Institute of Technology, Atlanta, Georgia, United States of America

Sarah R. Hosking

Roles Investigation

Affiliation Department of Infectious Diseases, College of Veterinary Medicine University of Georgia, Athens, Georgia, United States of America

Pramod Kumar E. K.

Roles Methodology, Resources

Affiliation Wallace H. Coulter Department of Biomedical Engineering, Emory University and Georgia Institute of Technology, Atlanta, Georgia, United States of America

Hyeyoon Jeong

Roles Investigation

Affiliation Wallace H. Coulter Department of Biomedical Engineering, Emory University and Georgia Institute of Technology, Atlanta, Georgia, United States of America

Younghun Jung

Roles Investigation

Affiliation Wallace H. Coulter Department of Biomedical Engineering, Emory University and Georgia Institute of Technology, Atlanta, Georgia, United States of America

José A. F. Assumpção

Roles Investigation

Affiliation Wallace H. Coulter Department of Biomedical Engineering, Emory University and Georgia Institute of Technology, Atlanta, Georgia, United States of America

Hannah E. Peck

Roles Resources

Affiliation Wallace H. Coulter Department of Biomedical Engineering, Emory University and Georgia Institute of Technology, Atlanta, Georgia, United States of America

Sarah L. Nelson

Roles Investigation

Affiliation Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, North Carolina, United States of America

Kaitlyn N. Burke

Roles Investigation

Affiliation Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, North Carolina, United States of America

McKinzie A. Garrison

Roles Methodology

Affiliation Emory Integrated Computational Core, Emory University, Atlanta, Georgia, United States of America

Robert A. Arthur

Roles Methodology

Affiliation Emory Integrated Computational Core, Emory University, Atlanta, Georgia, United States of America

Henry Claussen

Roles Methodology

Affiliation Emory Integrated Computational Core, Emory University, Atlanta, Georgia, United States of America

Nicholas S. Heaton

Roles Funding acquisition, Project administration, Supervision

Affiliations Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, North Carolina, United States of America, Duke Human Vaccine Institute Duke University School of Medicine, Durham, North Carolina, United States of America

Eric R. Lafontaine

Roles Formal analysis, Investigation, Project administration, Supervision

Affiliation Department of Infectious Diseases, College of Veterinary Medicine University of Georgia, Athens, Georgia, United States of America

Robert J. Hogan

Roles Funding acquisition, Investigation, Project administration, Supervision

Affiliation Department of Infectious Diseases, College of Veterinary Medicine University of Georgia, Athens, Georgia, United States of America

Chiara Zurla

Roles Funding acquisition, Investigation, Supervision, Visualization, Writing – original draft, Writing – review & editing

chiara.zurla@emory.edu (CZ); philip.j.santangelo@emory.edu (PJS)

Affiliation Wallace H. Coulter Department of Biomedical Engineering, Emory University and Georgia Institute of Technology, Atlanta, Georgia, United States of America

Philip J. Santangelo

Roles Funding acquisition, Project administration, Writing – original draft, Writing – review & editing

chiara.zurla@emory.edu (CZ); philip.j.santangelo@emory.edu (PJS)

Affiliation Wallace H. Coulter Department of Biomedical Engineering, Emory University and Georgia Institute of Technology, Atlanta, Georgia, United States of America

Competing Interests

D.V. and P.J.S. have a patent applied for regarding the polymer used in this work. D.V., C.Z. and P.J.S. have a provisional patent filed for the guides described in this work, and are co-founders of Tether Therapeutics. The terms of these arrangements have been reviewed and approved by Emory University in accordance with its conflict-of-interest policies. All other authors declare no competing interests.