About the Authors

Meredith A. Mortberg

Roles Data curation, Investigation, Writing – review & editing

Affiliation Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

Eric Vallabh Minikel

Roles Formal analysis, Funding acquisition, Investigation, Visualization, Writing – review & editing

Affiliations Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America, McCance Center for Brain Health, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, United States of America, Prion Alliance, Cambridge, Massachusetts, United States of America

Sonia M. Vallabh

Roles Conceptualization, Funding acquisition, Investigation, Supervision, Writing – original draft, Writing – review & editing

svallabh@broadinstitute.org

Affiliations Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America, McCance Center for Brain Health, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, United States of America, Prion Alliance, Cambridge, Massachusetts, United States of America

Competing Interests

I have read the journal’s policy and the authors of this manuscript have the following competing interests: SMV has received speaking fees from Ultragenyx, Illumina, and Biogen, and has received research support in the form of unrestricted charitable contributions from Ionis Pharmaceuticals. EVM has received consulting fees from Deerfield Management and has received research support in the form of unrestricted charitable contributions from Ionis Pharmaceuticals.