About the Authors

Marc Emmenegger

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Institute of Neuropathology, University of Zurich, Zurich, Switzerland

Sreedhar Saseendran Kumar

Contributed equally to this work with: Sreedhar Saseendran Kumar, Vishalini Emmenegger

Roles Data curation, Formal analysis, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Department of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland

Vishalini Emmenegger

Contributed equally to this work with: Sreedhar Saseendran Kumar, Vishalini Emmenegger

Roles Data curation, Formal analysis, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Department of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland

Tomas Malinauskas

Roles Investigation, Visualization, Writing – review & editing

Affiliation Division of Structural Biology, Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

Thomas Buettner

Roles Writing – review & editing

Affiliation GA Generic Assays GmbH, Dahlewitz, Germany

Laura Rose

Roles Investigation, Writing – review & editing

Affiliation GA Generic Assays GmbH, Dahlewitz, Germany

Peter Schierack

Roles Resources, Writing – review & editing

Affiliations Institute of Biotechnology, Faculty Environment and Natural Sciences, Brandenburg University of Technology Cottbus-Senftenberg, Senftenberg, Germany, Faculty of Health Sciences Brandenburg, University of Technology Cottbus-Senftenberg, Senftenberg, Germany

Martin F. Sprinzl

Roles Resources, Writing – review & editing

Affiliations Department of Internal Medicine I, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany, Institute of Clinical Chemistry and Laboratory Medicine, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany

Clemens J. Sommer

Roles Resources, Writing – review & editing

Affiliation Institute of Neuropathology, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany

Karl J. Lackner

Roles Resources, Writing – review & editing

Affiliation Institute of Clinical Chemistry and Laboratory Medicine, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany

Adriano Aguzzi

Roles Funding acquisition, Methodology, Resources, Supervision, Writing – review & editing

‡ These authors are joint senior authors on this work.

Affiliation Institute of Neuropathology, University of Zurich, Zurich, Switzerland

Dirk Roggenbuck

Roles Data curation, Formal analysis, Investigation, Methodology, Resources, Software, Supervision, Writing – original draft, Writing – review & editing

‡ These authors are joint senior authors on this work.

Affiliations GA Generic Assays GmbH, Dahlewitz, Germany, Institute of Biotechnology, Faculty Environment and Natural Sciences, Brandenburg University of Technology Cottbus-Senftenberg, Senftenberg, Germany, Faculty of Health Sciences Brandenburg, University of Technology Cottbus-Senftenberg, Senftenberg, Germany

Katrin B. M. Frauenknecht

Roles Conceptualization, Data curation, Formal analysis, Investigation, Project administration, Resources, Writing – original draft, Writing – review & editing

frauenknechtk@gmail.com

‡ These authors are joint senior authors on this work.

Affiliations Institute of Neuropathology, University of Zurich, Zurich, Switzerland, Institute of Neuropathology, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany

Competing Interests

I have read the journal’s policy and the authors of this manuscript have the following competing interests: DR has a management role and is a shareholder of GA Generic Assays GmbH and Medipan GmbH but no financial conflict of interest. Both companies are diagnostic manufacturers. LR and TB are employees of Generic Assays GmbH.