Extensive C->U transition biases in the genomes of a wide range of mammalian RNA viruses; potential associations with transcriptional mutations, damage- or host-mediated editing of viral RNA

Peter Simmonds; M. Azim Ansari

doi:10.1371/journal.ppat.1009596

Loading metrics

Open Access

Peer-reviewed

Research Article

Extensive C->U transition biases in the genomes of a wide range of mammalian RNA viruses; potential associations with transcriptional mutations, damage- or host-mediated editing of viral RNA

Peter Simmonds ,

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: Peter.simmonds@ndm.ox.ac.uk

Affiliation Nuffield Department of Medicine, Peter Medawar Building for Pathogen Research, University of Oxford, Oxford, United Kingdom

https://orcid.org/0000-0002-7964-4700

⨯
M. Azim Ansari

Roles Data curation, Funding acquisition, Investigation, Methodology, Resources, Software, Validation, Writing – review & editing

Affiliation Nuffield Department of Medicine, Peter Medawar Building for Pathogen Research, University of Oxford, Oxford, United Kingdom

https://orcid.org/0000-0003-2790-8353

⨯

Extensive C->U transition biases in the genomes of a wide range of mammalian RNA viruses; potential associations with transcriptional mutations, damage- or host-mediated editing of viral RNA

Peter Simmonds,
M. Azim Ansari

Published: June 1, 2021
https://doi.org/10.1371/journal.ppat.1009596

About the Authors

Peter Simmonds

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: Peter.simmonds@ndm.ox.ac.uk

Affiliation Nuffield Department of Medicine, Peter Medawar Building for Pathogen Research, University of Oxford, Oxford, United Kingdom

https://orcid.org/0000-0002-7964-4700

M. Azim Ansari

Roles Data curation, Funding acquisition, Investigation, Methodology, Resources, Software, Validation, Writing – review & editing

Affiliation Nuffield Department of Medicine, Peter Medawar Building for Pathogen Research, University of Oxford, Oxford, United Kingdom

https://orcid.org/0000-0003-2790-8353

Competing Interests

The authors have declared that no competing interests exist.

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

RNA viruses
Is the Subject Area "RNA viruses" applicable to this article?

Thanks for your feedback.
Microbial mutation
Is the Subject Area "Microbial mutation" applicable to this article?

Thanks for your feedback.
Coronaviruses
Is the Subject Area "Coronaviruses" applicable to this article?

Thanks for your feedback.
SARS CoV 2
Is the Subject Area "SARS CoV 2" applicable to this article?

Thanks for your feedback.
Sequence alignment
Is the Subject Area "Sequence alignment" applicable to this article?

Thanks for your feedback.
Genomics
Is the Subject Area "Genomics" applicable to this article?

Thanks for your feedback.
Rubella virus
Is the Subject Area "Rubella virus" applicable to this article?

Thanks for your feedback.
Viral genomics
Is the Subject Area "Viral genomics" applicable to this article?

Thanks for your feedback.