The Epstein-Barr virus miR-BHRF1-1 targets RNF4 during productive infection to promote the accumulation of SUMO conjugates and the release of infectious virus

Jinlin Li; Simone Callegari; Maria G. Masucci

doi:10.1371/journal.ppat.1006338

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Open Access

Peer-reviewed

Research Article

The Epstein-Barr virus miR-BHRF1-1 targets RNF4 during productive infection to promote the accumulation of SUMO conjugates and the release of infectious virus

Jinlin Li,

Affiliation Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden
⨯
Simone Callegari,

Affiliation Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden
⨯
Maria G. Masucci

* E-mail: maria.masucci@ki.se

Affiliation Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden

http://orcid.org/0000-0002-5541-2809

⨯

The Epstein-Barr virus miR-BHRF1-1 targets RNF4 during productive infection to promote the accumulation of SUMO conjugates and the release of infectious virus

Jinlin Li,
Simone Callegari,
Maria G. Masucci

Published: April 17, 2017
https://doi.org/10.1371/journal.ppat.1006338

About the Authors

Jinlin Li

Affiliation Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden

Simone Callegari

Affiliation Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden

Maria G. Masucci

* E-mail: maria.masucci@ki.se

Affiliation Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden

http://orcid.org/0000-0002-5541-2809

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceptualization: MGM. Formal analysis: SC. Funding acquisition: MGM. Investigation: JL SC. Supervision: MGM. Writing – original draft: JL SC MGM. Writing – review & editing: MGM.

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SUMOylation
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MicroRNAs
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Antibodies
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Epstein-Barr virus
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Luciferase
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Plasmid construction
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Doxycycline
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Viral replication
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