Localization of adenovirus morphogenesis players, together with visualization of assembly intermediates and failed products, favor a model where assembly and packaging occur concurrently at the periphery of the replication center

Gabriela N. Condezo; Carmen San Martín

doi:10.1371/journal.ppat.1006320

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Open Access

Peer-reviewed

Research Article

Localization of adenovirus morphogenesis players, together with visualization of assembly intermediates and failed products, favor a model where assembly and packaging occur concurrently at the periphery of the replication center

Gabriela N. Condezo,

Affiliation Department of Macromolecular Structures, Centro Nacional de Biotecnología (CNB-CSIC), Madrid, Spain

http://orcid.org/0000-0003-2884-0661

⨯
Carmen San Martín

* E-mail: carmen@cnb.csic.es

Affiliation Department of Macromolecular Structures, Centro Nacional de Biotecnología (CNB-CSIC), Madrid, Spain

http://orcid.org/0000-0001-9799-175X

⨯

Localization of adenovirus morphogenesis players, together with visualization of assembly intermediates and failed products, favor a model where assembly and packaging occur concurrently at the periphery of the replication center

Gabriela N. Condezo,
Carmen San Martín

Published: April 27, 2017
https://doi.org/10.1371/journal.ppat.1006320

About the Authors

Gabriela N. Condezo

Affiliation Department of Macromolecular Structures, Centro Nacional de Biotecnología (CNB-CSIC), Madrid, Spain

http://orcid.org/0000-0003-2884-0661

Carmen San Martín

* E-mail: carmen@cnb.csic.es

Affiliation Department of Macromolecular Structures, Centro Nacional de Biotecnología (CNB-CSIC), Madrid, Spain

http://orcid.org/0000-0001-9799-175X

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceptualization: GNC CSM. Formal analysis: GNC CSM. Funding acquisition: CSM. Investigation: GNC. Project administration: GNC CSM. Supervision: CSM. Visualization: GNC CSM. Writing – original draft: GNC CSM. Writing – review & editing: GNC CSM.

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Viral packaging
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Viral core
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Virions
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Viral replication
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Bromodeoxyuridine labeling
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DNA replication
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Genomics
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Viral genomics
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