About the Authors

Elisabetta Groppelli

Affiliation School of Molecular and Cellular Biology & Astbury Centre for Structural Molecular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, West Yorkshire, United Kingdom

Hazel C. Levy

Current address: Child Health Research Institute, Department of Pediatrics, College of Medicine, University of Florida, Gainesville, Florida, United States of America

Affiliation Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, United States of America

Eileen Sun

Current address: Aspyrian Therapeutics, San Diego, California, United States of America

Affiliation Program in Virology and Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts, United States of America

Mike Strauss

Current address: Max-Planck-Institute for Biochemistry, Martinsried, Germany

Affiliation Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, United States of America

Clare Nicol

Affiliation School of Molecular and Cellular Biology & Astbury Centre for Structural Molecular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, West Yorkshire, United Kingdom

Sarah Gold

Affiliation The Pirbright Institute, Pirbright, Surrey, United Kingdom

Xiaowei Zhuang

Affiliation Howard Hughes Institute and Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts, United States of America

Tobias J. Tuthill

Affiliation The Pirbright Institute, Pirbright, Surrey, United Kingdom

James M. Hogle

james_hogle@hms.harvard.edu (JMH); d.j.rowlands@leeds.ac.uk (DJR)

Affiliation Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, United States of America

David J. Rowlands

james_hogle@hms.harvard.edu (JMH); d.j.rowlands@leeds.ac.uk (DJR)

Affiliation School of Molecular and Cellular Biology & Astbury Centre for Structural Molecular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, West Yorkshire, United Kingdom

Competing Interests

I have read the journal's policy and the authors of this manuscript have the following competing interests: Eileen Sun now works for Aspyrian Therapeutics.

Author Contributions

Conceptualization: JMH DJR. Formal analysis: EG HCL ES MS. Funding acquisition: DJR JMH TJT MS. Investigation: EG HCL ES MS CN SG TJT. Methodology: EG HCL ES MS CN SG XZ TJT JMH DJR. Project administration: DJR JMH TJT EG. Supervision: DJR JMH TJT. Visualization: EG MS HCL ES SG TJT. Writing – original draft: EG MS TJT JMH DJR. Writing – review & editing: EG MS TJT JMH DJR.