About the Authors

George J. Leslie

Contributed equally to this work with: George J. Leslie, Jianbin Wang, Max W. Richardson

Affiliation Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States of America

Jianbin Wang

Contributed equally to this work with: George J. Leslie, Jianbin Wang, Max W. Richardson

Affiliation Sangamo BioSciences Inc., Richmond, CA, United States of America

Max W. Richardson

Contributed equally to this work with: George J. Leslie, Jianbin Wang, Max W. Richardson

Affiliation Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States of America

Beth S. Haggarty

Affiliation Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States of America

Kevin L. Hua

Affiliation Sangamo BioSciences Inc., Richmond, CA, United States of America

Jennifer Duong

Affiliation Sangamo BioSciences Inc., Richmond, CA, United States of America

Anthony J. Secreto

Affiliation Department of Pathology & Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States of America

Andrea P. O. Jordon

Affiliation Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States of America

Josephine Romano

Affiliation Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States of America

Kritika E. Kumar

Affiliation Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States of America

Joshua J. DeClercq

Affiliation Sangamo BioSciences Inc., Richmond, CA, United States of America

Philip D. Gregory

Affiliation Sangamo BioSciences Inc., Richmond, CA, United States of America

Carl H. June

Affiliation Department of Pathology & Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States of America

Michael J. Root

Affiliation Department of Biochemistry and Molecular Biology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA, United States of America

James L. Riley

Affiliation Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States of America

Michael C. Holmes

Affiliation Sangamo BioSciences Inc., Richmond, CA, United States of America

James A. Hoxie

hoxie@mail.med.upenn.edu

Affiliation Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States of America

Competing Interests

I have read the journal's policy and the authors of this manuscript have the following competing interests: JW, JJD, MCH, KLH, JD, and PDG are employees of Sangamo Biosciences Inc.

Author Contributions

Conceived and designed the experiments: GJL JW MWR PDG CHJ MJR JLR MCH JAH. Performed the experiments: GJL JW MWR BSH KLH JD AJS APOJ JR KEK JJD MJR. Analyzed the data: GJL JW MWR MJR MCH JAH. Contributed reagents/materials/analysis tools: MJR. Wrote the paper: GJL JW MWR MJR JLR MCH JAH.