About the Authors

P. J. Klasse

Affiliation Department of Microbiology and Immunology, Weill Medical College of Cornell University, New York, New York, United States of America

Celia C. LaBranche

Contributed equally to this work with: Celia C. LaBranche, Thomas J. Ketas

Affiliation Department of Surgery, Duke University Medical Center, Durham, North Carolina, United States of America

Thomas J. Ketas

Contributed equally to this work with: Celia C. LaBranche, Thomas J. Ketas

Affiliation Department of Microbiology and Immunology, Weill Medical College of Cornell University, New York, New York, United States of America

Gabriel Ozorowski

Affiliation Department of Integrative Structural and Computational Biology, International AIDS Vaccine Initiative (IAVI) Neutralizing Antibody Center and the Collaboration for AIDS Vaccine Discovery (CAVD), The Scripps Research Institute, La Jolla, California, United States of America

Albert Cupo

Affiliation Department of Microbiology and Immunology, Weill Medical College of Cornell University, New York, New York, United States of America

Pavel Pugach

Affiliation Department of Microbiology and Immunology, Weill Medical College of Cornell University, New York, New York, United States of America

Rajesh P. Ringe

Affiliation Department of Microbiology and Immunology, Weill Medical College of Cornell University, New York, New York, United States of America

Michael Golabek

Affiliation Department of Microbiology and Immunology, Weill Medical College of Cornell University, New York, New York, United States of America

Marit J. van Gils

Affiliations Department of Integrative Structural and Computational Biology, International AIDS Vaccine Initiative (IAVI) Neutralizing Antibody Center and the Collaboration for AIDS Vaccine Discovery (CAVD), The Scripps Research Institute, La Jolla, California, United States of America, Department of Medical Microbiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

Miklos Guttman

Affiliation Department of Medicinal Chemistry, University of Washington, Seattle, Washington, United States of America

Kelly K. Lee

Affiliation Department of Medicinal Chemistry, University of Washington, Seattle, Washington, United States of America

Ian A. Wilson

Affiliations Department of Integrative Structural and Computational Biology, International AIDS Vaccine Initiative (IAVI) Neutralizing Antibody Center and the Collaboration for AIDS Vaccine Discovery (CAVD), The Scripps Research Institute, La Jolla, California, United States of America, Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, California, United States of America, The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California, United States of America

Salvatore T. Butera

Affiliation Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, California, United States of America

Andrew B. Ward

Affiliations Department of Integrative Structural and Computational Biology, International AIDS Vaccine Initiative (IAVI) Neutralizing Antibody Center and the Collaboration for AIDS Vaccine Discovery (CAVD), The Scripps Research Institute, La Jolla, California, United States of America, Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, California, United States of America

David C. Montefiori

Affiliation Department of Surgery, Duke University Medical Center, Durham, North Carolina, United States of America

Rogier W. Sanders

rws2002@med.cornell.edu (RWS); jpm2003@med.cornell.edu (JPM)

Affiliations Department of Microbiology and Immunology, Weill Medical College of Cornell University, New York, New York, United States of America, Department of Medical Microbiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

John P. Moore

rws2002@med.cornell.edu (RWS); jpm2003@med.cornell.edu (JPM)

Affiliation Department of Microbiology and Immunology, Weill Medical College of Cornell University, New York, New York, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: PJK IAW ABW STB RWS JPM. Performed the experiments: CCL DCM TJK. Analyzed the data: PJK DCM IAW ABW JPM. Contributed reagents/materials/analysis tools: AC MGo RPR PP GO MJvG KKL MGu. Wrote the paper: PJK DCM IAW ABW RWS JPM. Funded and supervised the study: PJK KKL DCM IAW ABW STB RWS JPM.