About the Authors

Victoria A. Meliopoulos

Contributed equally to this work with: Victoria A. Meliopoulos, Lee-Ann Van de Velde

Affiliation Department of Infectious Diseases, St Jude Children’s Research Hospital, Memphis, Tennessee, United States of America

Lee-Ann Van de Velde

Contributed equally to this work with: Victoria A. Meliopoulos, Lee-Ann Van de Velde

Affiliations Department of Infectious Diseases, St Jude Children’s Research Hospital, Memphis, Tennessee, United States of America, Department of Immunology, St Jude Children’s Research Hospital, Memphis, Tennessee, United States of America

Nicholas C. Van de Velde

Affiliations Department of Infectious Diseases, St Jude Children’s Research Hospital, Memphis, Tennessee, United States of America, Department of Immunology, St Jude Children’s Research Hospital, Memphis, Tennessee, United States of America

Erik A. Karlsson

Affiliation Department of Infectious Diseases, St Jude Children’s Research Hospital, Memphis, Tennessee, United States of America

Geoff Neale

Affiliation The Hartwell Center, St Jude Children’s Research Hospital, Memphis, Tennessee, United States of America

Peter Vogel

Affiliation Department of Veterinary Pathology Core, St Jude Children’s Research Hospital, Memphis, Tennessee, United States of America

Cliff Guy

Affiliation Department of Immunology, St Jude Children’s Research Hospital, Memphis, Tennessee, United States of America

Shalini Sharma

Affiliation Department of Immunology, St Jude Children’s Research Hospital, Memphis, Tennessee, United States of America

Susu Duan

Affiliation Department of Immunology, St Jude Children’s Research Hospital, Memphis, Tennessee, United States of America

Sherri L. Surman

Affiliation Department of Infectious Diseases, St Jude Children’s Research Hospital, Memphis, Tennessee, United States of America

Bart G. Jones

Affiliation Department of Infectious Diseases, St Jude Children’s Research Hospital, Memphis, Tennessee, United States of America

Michael D. L. Johnson

Affiliation Department of Infectious Diseases, St Jude Children’s Research Hospital, Memphis, Tennessee, United States of America

Catharine Bosio

Affiliation Rocky Mountain Laboratories, NIAID, NIH, Hamilton, Montana, United States of America

Lisa Jolly

Affiliation Division of Respiratory Medicine, University of Nottingham, Nottingham, United Kingdom

R. Gisli Jenkins

Affiliation Division of Respiratory Medicine, University of Nottingham, Nottingham, United Kingdom

Julia L. Hurwitz

Affiliation Department of Infectious Diseases, St Jude Children’s Research Hospital, Memphis, Tennessee, United States of America

Jason W. Rosch

Affiliation Department of Infectious Diseases, St Jude Children’s Research Hospital, Memphis, Tennessee, United States of America

Dean Sheppard

Affiliation Department of Medicine, Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, UCSF Medical Center, San Francisco, California, United States of America

Paul G. Thomas

Affiliation Department of Immunology, St Jude Children’s Research Hospital, Memphis, Tennessee, United States of America

Peter J. Murray

peter.murray@stjude.org (PJM); Stacey.Schultz-Cherry@stjude.org (SSC)

Affiliations Department of Infectious Diseases, St Jude Children’s Research Hospital, Memphis, Tennessee, United States of America, Department of Immunology, St Jude Children’s Research Hospital, Memphis, Tennessee, United States of America

Stacey Schultz-Cherry

peter.murray@stjude.org (PJM); Stacey.Schultz-Cherry@stjude.org (SSC)

Affiliation Department of Infectious Diseases, St Jude Children’s Research Hospital, Memphis, Tennessee, United States of America

Competing Interests

RGJ has acted as a consultant for GSK, Boehringer Ingelheim, Intermune, Medimmune, Biogen Idec and Pulmatrix and has research contracts with GSK, Novartis, and Biogen Idec. DS has a research agreement with Biogen Idec and is a co-inventor on a patent on blocking αVβ6 to prevent acute lung injury.

Author Contributions

Conceived and designed the experiments: VAM LAVdV NCVdV PJM SSC. Performed the experiments: VAM LAVdV NCVdV EAK CG SS SD SLS BGJ MDLJ CB LJ. Analyzed the data: VAM LAVdV GN. Contributed reagents/materials/analysis tools: GN PV CG RGJ JLH JWR DS PGT PJM SSC. Wrote the paper: VAM LAVdV SSC PJM.